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Spontaneous pregnancy rates in Chinese men undergoing microsurgical subinguinal varicocelectomy and possible preoperative factors affecting the outcomes
Peng, Jing1; Zhang, Zhichao1; Cui, Wanshou1; Yuan, Yiming1; Song, Weidong1; Gao, Bing1; Xin, Zhongcheng1; Zhu, Sainan2
关键词Male infertility varicocele pregnancy microsurgery
刊名FERTILITY AND STERILITY
2015-03-01
DOI10.1016/j.fertnstert.2014.12.091
103期:3页:635-639
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Obstetrics & Gynecology ; Reproductive Biology
研究领域[WOS]Obstetrics & Gynecology ; Reproductive Biology
关键词[WOS]ASSISTED REPRODUCTIVE TECHNOLOGY ; MALE-INFERTILITY ; SEMEN ; METAANALYSIS ; COUPLES ; REPAIR
英文摘要

Objective: To investigate pregnancy rates after microsurgical varicocelectomy in Chinese infertile men with clinical varicoceles and to identify preoperative factors affecting the outcomes.

Design: Retrospective data analysis.

Setting: University infertility clinic.

Patient(s): One hundred seventy-six consecutive Chinese men with infertility and clinical varicoceles who underwent varicocelectomy from January 2010 to December 2011. Semen data were available for 145 patients, and pregnancy data were available for 66.

Intervention(s): Varicocelectomy was performed on all patients.

Main Outcome Measure(s): Spontaneous pregnancy rates and improvement in semen parameters after varicocelectomy.

Result(s): We followed 145 men (82.4%) for a median of 21 months (range 12-36 months) after varicocelectomy. For 109 patients (75.2%), both sperm concentration and forward motility improved. Overall, 45.5% (66/145) of female partners achieved spontaneous pregnancy at a mean follow-up of 11.7 +/- 6.2 months. On univariate analysis, preoperative high sperm concentration (>= 20 million/mL) and high sperm motility (>= 25%) were positively associated with spontaneous pregnancy. On multivariate analysis, only preoperative sperm concentration was an independent predictor.

Conclusion(s): Microsurgical varicocelectomy could improve semen quality and spontaneous pregnancy rates. Only preoperative sperm concentration was an independent predictor of spontaneous pregnancy. Patients with high initial sperm concentration may benefit from varicocelectomy for spontaneous pregnancy. ((c) 2015 by American Society for Reproductive Medicine.)

语种英语
WOS记录号WOS:000352109000012
引用统计
被引频次:10[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/59151
专题北京大学第一临床医学院_男科中心
北京大学第一临床医学院_泌尿外科
北京大学第一临床医学院_医学统计室
作者单位1.Peking Univ, Hosp 1, Dept Biostat, Beijing 100034, Peoples R China
2.Peking Univ, Hosp 1, Androl Ctr, Beijing 100034, Peoples R China
推荐引用方式
GB/T 7714
Peng, Jing,Zhang, Zhichao,Cui, Wanshou,et al. Spontaneous pregnancy rates in Chinese men undergoing microsurgical subinguinal varicocelectomy and possible preoperative factors affecting the outcomes[J]. FERTILITY AND STERILITY,2015,103(3):635-639.
APA Peng, Jing.,Zhang, Zhichao.,Cui, Wanshou.,Yuan, Yiming.,Song, Weidong.,...&Zhu, Sainan.(2015).Spontaneous pregnancy rates in Chinese men undergoing microsurgical subinguinal varicocelectomy and possible preoperative factors affecting the outcomes.FERTILITY AND STERILITY,103(3),635-639.
MLA Peng, Jing,et al."Spontaneous pregnancy rates in Chinese men undergoing microsurgical subinguinal varicocelectomy and possible preoperative factors affecting the outcomes".FERTILITY AND STERILITY 103.3(2015):635-639.
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