北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学临床肿瘤学院  > 期刊论文
学科主题: 临床医学
题名:
Synchrotron-radiation phase-contrast imaging of human stomach and gastric cancer: in vitro studies
作者: Tang, Lei1; Li, Gang2; Sun, Ying-Shi1; Li, Jie1; Zhang, Xiao-Peng1
关键词: phase contrast ; X-ray ; stomach ; neoplasm
刊名: JOURNAL OF SYNCHROTRON RADIATION
发表日期: 2012-05-01
DOI: 10.1107/S090904951200310X
卷: 19, 页:319-322
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Instruments & Instrumentation ; Optics ; Physics, Applied
研究领域[WOS]: Instruments & Instrumentation ; Optics ; Physics
关键词[WOS]: X-RAY CT ; BREAST-TUMOR ; REFRACTION ; VISUALIZATION ; TOMOGRAPHY
英文摘要:

The electron density resolution of synchrotron-radiation phase-contrast imaging (SR-PCI) is 1000 times higher than that of conventional X-ray absorption imaging in light elements, through which high-resolution X-ray imaging of biological soft tissue can be achieved. For biological soft tissue, SR-PCI can give better imaging contrast than conventional X-ray absorption imaging. In this study, human resected stomach and gastric cancer were investigated using in-line holography and diffraction enhanced imaging at beamline 4W1A of the Beijing Synchrotron Radiation Facility. It was possible to depict gastric pits, measuring 5070 mu m, gastric grooves and tiny blood vessels in the submucosa layer by SR-PCI. The fine structure of a cancerous ulcer was displayed clearly on imaging the mucosa. The delamination of the gastric wall and infiltration of cancer in the submucosa layer were also demonstrated on cross-sectional imaging. In conclusion, SR-PCI can demonstrate the subtle structures of stomach and gastric cancer that cannot be detected by conventional X-ray absorption imaging, which prompt the X-ray diagnosis of gastric disease to the level of the gastric pit, and has the potential to provide new methods for the imageology of gastric cancer.

语种: 英语
所属项目编号: 2011CB707705 ; 30970825 ; 7092020
项目资助者: National Basic Research Program of China (973 Program) ; National Natural Science Foundation of China ; Natural Science Foundation of Beijing, China
WOS记录号: WOS:000302998900003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59172
Appears in Collections:北京大学临床肿瘤学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Peking Univ, Sch Oncol, Beijing Canc Hosp & Inst, Key Lab Carcinogenesis & Translat Res,Minist Educ, Beijing 100142, Peoples R China
2.Chinese Acad Sci, Inst High Energy Phys, Beijing Synchrotron Radiat Facil, Beijing 100049, Peoples R China

Recommended Citation:
Tang, Lei,Li, Gang,Sun, Ying-Shi,et al. Synchrotron-radiation phase-contrast imaging of human stomach and gastric cancer: in vitro studies[J]. JOURNAL OF SYNCHROTRON RADIATION,2012,19:319-322.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Tang, Lei]'s Articles
[Li, Gang]'s Articles
[Sun, Ying-Shi]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Tang, Lei]‘s Articles
[Li, Gang]‘s Articles
[Sun, Ying-Shi]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace