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学科主题临床医学
Atopic dermatitis-like presentation of graft-versus-host disease: A novel form of chronic cutaneous graft-versus-host disease
Wei, Jin1; Zhang, Yu2; Xu, Hongjun1; Jin, Jiang1; Zhang, Jianzhong1
关键词atopic dermatitis graft-versus-host disease
刊名JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
2013-07-01
DOI10.1016/j.jaad.2012.12.970
69期:1页:34-39
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Dermatology
研究领域[WOS]Dermatology
关键词[WOS]SKIN
英文摘要

Background: Graft-versus-host disease (GVHD) is a systemic disease, and skin is often one of the target organs. An atopic dermatitis (AD)-like presentation has never to our knowledge been reported.

Objective: We sought to describe an AD-like presentation of cutaneous GVHD.

Methods: Data on 11 patients with an AD-like presentation of GVHD were collected. The clinical and laboratory findings were retrospectively studied.

Results: All 11 patients developed skin lesions after hematopoietic stem-cell transplantation. The skin lesions occurred between 2 to 12 months after transplantation. Eight patients received their transplant from a first-degree family member; 3 received their transplant from an unrelated donor. The skin lesions were pruritic and suggestive of AD, whereas the histology showed features of AD and GVHD. The lesions responded to topical and systemic anti-inflammatory and immunosuppressive therapy and phototherapy.

Limitations: The number of patients is small and the study is retrospective.

Conclusions: AD-like GVHD might represent a novel form of chronic cutaneous GVHD and responds well to treatment.

语种英语
WOS记录号WOS:000320510100019
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/59243
专题北京大学第二临床医学院_皮科
作者单位1.Peking Univ Peoples Hosp, Dept Dermatol, Beijing, Peoples R China
2.China Aerosp 731 Hosp, Dept Dermatol, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Wei, Jin,Zhang, Yu,Xu, Hongjun,et al. Atopic dermatitis-like presentation of graft-versus-host disease: A novel form of chronic cutaneous graft-versus-host disease[J]. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY,2013,69(1):34-39.
APA Wei, Jin,Zhang, Yu,Xu, Hongjun,Jin, Jiang,&Zhang, Jianzhong.(2013).Atopic dermatitis-like presentation of graft-versus-host disease: A novel form of chronic cutaneous graft-versus-host disease.JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY,69(1),34-39.
MLA Wei, Jin,et al."Atopic dermatitis-like presentation of graft-versus-host disease: A novel form of chronic cutaneous graft-versus-host disease".JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY 69.1(2013):34-39.
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