|Histochemical study of transmyocardial laser channels in dogs|
|Lei, L; Guo, JX; Liu, DG; Zhao, R; Chen, FR; Mao, JM; Zhang, P; Bai, RY|
|关键词||histochemistry lactate dehydrogenase succinate dehydrogenase transmyocardial revascularization laser|
|刊名||CHINESE MEDICAL JOURNAL|
|WOS标题词||Science & Technology|
|类目[WOS]||Medicine, General & Internal|
|研究领域[WOS]||General & Internal Medicine|
|关键词[WOS]||MYOCARDIAL REVASCULARIZATION ; DAMAGE|
Objective Laser-induced myocardial injury was investigated in a canine transmyocardial laser revascularization model.
Methods A total of 23 channels were created in the left ventricles of 5 animals with a CO2 laser. Four animals were sacrificed immediately and one at week 2. Lactate dehydrogenase and succinate dehydrogenase in channel regions were examined with a Nitro-BT method staining.
Results Immediately after the procedure, laser channels and surrounding injured myocardium could be stratified from the center to the border into 5 concentric zones, i.e., vaporized zone, carbonized zone, enzyme-disappeared zone, enzyme-decreased zone and enzyme-concentrated zone. Two weeks later, the phenomenon disappeared.
Conclusions Immediately after transmyocardial revascularization, there is a ring of enzyme-concentrated zone at the outermost region of injured myocardium. Two weeks later, enzyme activities of reversibly injured myocytes appear to have recovered.
|作者单位||Beijing Univ, Sch Med, Hosp 3, Dept Cardiol, Beijing 100083, Peoples R China|
|Lei, L,Guo, JX,Liu, DG,et al. Histochemical study of transmyocardial laser channels in dogs[J]. CHINESE MEDICAL JOURNAL,2001,114(9):902-905.|
|APA||Lei, L.,Guo, JX.,Liu, DG.,Zhao, R.,Chen, FR.,...&Bai, RY.(2001).Histochemical study of transmyocardial laser channels in dogs.CHINESE MEDICAL JOURNAL,114(9),902-905.|
|MLA||Lei, L,et al."Histochemical study of transmyocardial laser channels in dogs".CHINESE MEDICAL JOURNAL 114.9(2001):902-905.|