IR@PKUHSC  > 北京大学第三临床医学院  > 心血管内科
学科主题临床医学
Histochemical study of transmyocardial laser channels in dogs
Lei, L; Guo, JX; Liu, DG; Zhao, R; Chen, FR; Mao, JM; Zhang, P; Bai, RY
关键词histochemistry lactate dehydrogenase succinate dehydrogenase transmyocardial revascularization laser
刊名CHINESE MEDICAL JOURNAL
2001-09-01
114期:9页:902-905
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal
研究领域[WOS]General & Internal Medicine
关键词[WOS]MYOCARDIAL REVASCULARIZATION ; DAMAGE
英文摘要

Objective Laser-induced myocardial injury was investigated in a canine transmyocardial laser revascularization model.

Methods A total of 23 channels were created in the left ventricles of 5 animals with a CO2 laser. Four animals were sacrificed immediately and one at week 2. Lactate dehydrogenase and succinate dehydrogenase in channel regions were examined with a Nitro-BT method staining.

Results Immediately after the procedure, laser channels and surrounding injured myocardium could be stratified from the center to the border into 5 concentric zones, i.e., vaporized zone, carbonized zone, enzyme-disappeared zone, enzyme-decreased zone and enzyme-concentrated zone. Two weeks later, the phenomenon disappeared.

Conclusions Immediately after transmyocardial revascularization, there is a ring of enzyme-concentrated zone at the outermost region of injured myocardium. Two weeks later, enzyme activities of reversibly injured myocytes appear to have recovered.

语种英语
WOS记录号WOS:000171143400002
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/59284
Collection北京大学第三临床医学院_心血管内科
作者单位Beijing Univ, Sch Med, Hosp 3, Dept Cardiol, Beijing 100083, Peoples R China
Recommended Citation
GB/T 7714
Lei, L,Guo, JX,Liu, DG,et al. Histochemical study of transmyocardial laser channels in dogs[J]. CHINESE MEDICAL JOURNAL,2001,114(9):902-905.
APA Lei, L.,Guo, JX.,Liu, DG.,Zhao, R.,Chen, FR.,...&Bai, RY.(2001).Histochemical study of transmyocardial laser channels in dogs.CHINESE MEDICAL JOURNAL,114(9),902-905.
MLA Lei, L,et al."Histochemical study of transmyocardial laser channels in dogs".CHINESE MEDICAL JOURNAL 114.9(2001):902-905.
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