IR@PKUHSC  > 北京大学第二临床医学院
学科主题临床医学
Serum Lipids and Lipoproteins in Chinese Men and Women
Yang, Wenying1; Xiao, Jianzhong; Yang, Zhaojun; Ji, Linong2; Jia, Weiping3; Weng, Jianping4; Lu, Juming5; Shan, Zhongyan6; Liu, Jie; Tian, Haoming; Ji, Qiuhe; Zhu, Dalong7; Ge, Jiapu8; Lin, Lixiang9; Chen, Li; Guo, Xiaohui10; Zhao, Zhigang; Li, Qiang11; Zhou, Zhiguang; Shan, Guangliang12; He, Jiang13; China Natl Diabet Metab Disorders
关键词China cross-sectional studies lipids lipoproteins prevalence
刊名CIRCULATION
2012-05-08
DOI10.1161/CIRCULATIONAHA.111.065904
125期:18页:2212-2221
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Cardiac & Cardiovascular Systems ; Peripheral Vascular Disease
研究领域[WOS]Cardiovascular System & Cardiology
关键词[WOS]REPUBLIC-OF-CHINA ; DISEASE RISK-FACTORS ; CHOLESTEROL CONCENTRATIONS ; CORONARY ; REDUCTION ; HEALTH ; TRENDS ; ADULTS ; HYPERCHOLESTEROLEMIA ; METAANALYSIS
英文摘要

Background-Because of rapid change in lifestyle risk factors, cardiovascular disease has become the leading cause of death in China. We sought to estimate the national levels of serum lipids and lipoproteins among the Chinese adult population.

Methods and Results-We conducted a cross-sectional study in a nationally representative sample of 46 239 adults aged >= 20 years. Fasting serum total, high-density lipoprotein, and low-density lipoprotein cholesterol and triglycerides were measured by standard methods. The age-standardized estimates of total, high-density lipoprotein, and low-density lipoprotein cholesterol and triglycerides were 4.72 (95% confidence interval, 4.70-4.73), 1.30 (1.29-1.30), 2.68 (2.67-2.70), and 1.57 (1.55-1.58) mmol/L, respectively, in the Chinese adult population. In addition, 22.5% (21.8-23.3%) or 220.4 million (212.1-228.8) Chinese adults had borderline high total cholesterol (5.18-6.21 mmol/L), and 9.0% (8.5-9.5%) or 88.1 million (83.4-92.8) had high total cholesterol (> 6.22 mmol/L). The population estimates for borderline high (3.37-4.13 mmol/L), high (4.14-4.91 mmol/L), and very high (>= 4.92 mmol/L) low-density lipoprotein cholesterol were 13.9% (13.3-14.5%) or 133.5 million (127.0-140.1), 3.5% (3.3-3.8%) or 33.8 million (31.2-36.5), and 3.0% (2.8-3.3%) or 29.0 million (26.3-31.8) persons, respectively. In addition, 22.3% (21.6-23.1%) or 214.9 million (207.0-222.8) persons had low high-density lipoprotein cholesterol (<1.04 mmol/L). The awareness, treatment, and control of borderline high or high total cholesterol were 11.0%, 5.1%, and 2.8%, respectively, in the Chinese adult population.

Conclusions-Serum total and low-density lipoprotein cholesterol levels were high and increasing in the Chinese population. Without effective intervention, atherosclerotic cardiovascular diseases may soar in the near future in China. (Circulation. 2012;125:2212-2221.)

语种英语
WOS记录号WOS:000306962600014
资助机构Chinese Medical Association Foundation ; Chinese Diabetes Society
引用统计
被引频次:66[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/59354
专题北京大学第二临床医学院
北京大学第一临床医学院_内分泌内科
作者单位1.China Japan Friendship Hosp, Dept Endocrinol, Beijing 100029, Peoples R China
2.Peking Univ, Peoples Hosp, Beijing 100871, Peoples R China
3.Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Shanghai 200030, Peoples R China
4.Sun Yat Sen Univ, Hosp 3, Guangzhou 510275, Guangdong, Peoples R China
5.Chinese Peoples Liberat Army Gen Hosp, Beijing, Peoples R China
6.Chinese Med Univ, Affiliated Hosp 1, Liaoling, Peoples R China
7.Nanjing Univ, Sch Med, Affiliated Drum Tower Hosp, Nanjing, Jiangsu, Peoples R China
8.Xinjiang Uygur Autonomous Reg Hosp, Xinjiang, Peoples R China
9.Fujian Prov Hosp, Fujiang, Peoples R China
10.Peking Univ, Hosp 1, Beijing 100871, Peoples R China
11.Harbin Med Univ, Affiliated Hosp 2, Harbin, Heilongjiang, Peoples R China
12.Peking Union Med Coll, Beijing 100021, Peoples R China
13.Tulane Univ, Sch Publ Hlth & Trop Med, New Orleans, LA USA
推荐引用方式
GB/T 7714
Yang, Wenying,Xiao, Jianzhong,Yang, Zhaojun,et al. Serum Lipids and Lipoproteins in Chinese Men and Women[J]. CIRCULATION,2012,125(18):2212-2221.
APA Yang, Wenying.,Xiao, Jianzhong.,Yang, Zhaojun.,Ji, Linong.,Jia, Weiping.,...&China Natl Diabet Metab Disorders.(2012).Serum Lipids and Lipoproteins in Chinese Men and Women.CIRCULATION,125(18),2212-2221.
MLA Yang, Wenying,et al."Serum Lipids and Lipoproteins in Chinese Men and Women".CIRCULATION 125.18(2012):2212-2221.
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