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学科主题: 临床医学
题名:
Serum Lipids and Lipoproteins in Chinese Men and Women
作者: Yang, Wenying1; Xiao, Jianzhong; Yang, Zhaojun; Ji, Linong2; Jia, Weiping3; Weng, Jianping4; Lu, Juming5; Shan, Zhongyan6; Liu, Jie; Tian, Haoming; Ji, Qiuhe; Zhu, Dalong7; Ge, Jiapu8; Lin, Lixiang9; Chen, Li; Guo, Xiaohui10; Zhao, Zhigang; Li, Qiang11; Zhou, Zhiguang; Shan, Guangliang12; He, Jiang13; China Natl Diabet Metab Disorders
关键词: China ; cross-sectional studies ; lipids ; lipoproteins ; prevalence
刊名: CIRCULATION
发表日期: 2012-05-08
DOI: 10.1161/CIRCULATIONAHA.111.065904
卷: 125, 期:18, 页:2212-2221
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Cardiac & Cardiovascular Systems ; Peripheral Vascular Disease
研究领域[WOS]: Cardiovascular System & Cardiology
关键词[WOS]: REPUBLIC-OF-CHINA ; DISEASE RISK-FACTORS ; CHOLESTEROL CONCENTRATIONS ; CORONARY ; REDUCTION ; HEALTH ; TRENDS ; ADULTS ; HYPERCHOLESTEROLEMIA ; METAANALYSIS
英文摘要:

Background-Because of rapid change in lifestyle risk factors, cardiovascular disease has become the leading cause of death in China. We sought to estimate the national levels of serum lipids and lipoproteins among the Chinese adult population.

Methods and Results-We conducted a cross-sectional study in a nationally representative sample of 46 239 adults aged >= 20 years. Fasting serum total, high-density lipoprotein, and low-density lipoprotein cholesterol and triglycerides were measured by standard methods. The age-standardized estimates of total, high-density lipoprotein, and low-density lipoprotein cholesterol and triglycerides were 4.72 (95% confidence interval, 4.70-4.73), 1.30 (1.29-1.30), 2.68 (2.67-2.70), and 1.57 (1.55-1.58) mmol/L, respectively, in the Chinese adult population. In addition, 22.5% (21.8-23.3%) or 220.4 million (212.1-228.8) Chinese adults had borderline high total cholesterol (5.18-6.21 mmol/L), and 9.0% (8.5-9.5%) or 88.1 million (83.4-92.8) had high total cholesterol (> 6.22 mmol/L). The population estimates for borderline high (3.37-4.13 mmol/L), high (4.14-4.91 mmol/L), and very high (>= 4.92 mmol/L) low-density lipoprotein cholesterol were 13.9% (13.3-14.5%) or 133.5 million (127.0-140.1), 3.5% (3.3-3.8%) or 33.8 million (31.2-36.5), and 3.0% (2.8-3.3%) or 29.0 million (26.3-31.8) persons, respectively. In addition, 22.3% (21.6-23.1%) or 214.9 million (207.0-222.8) persons had low high-density lipoprotein cholesterol (<1.04 mmol/L). The awareness, treatment, and control of borderline high or high total cholesterol were 11.0%, 5.1%, and 2.8%, respectively, in the Chinese adult population.

Conclusions-Serum total and low-density lipoprotein cholesterol levels were high and increasing in the Chinese population. Without effective intervention, atherosclerotic cardiovascular diseases may soar in the near future in China. (Circulation. 2012;125:2212-2221.)

语种: 英语
项目资助者: Chinese Medical Association Foundation ; Chinese Diabetes Society
WOS记录号: WOS:000306962600014
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59354
Appears in Collections:北京大学第二临床医学院_期刊论文

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作者单位: 1.China Japan Friendship Hosp, Dept Endocrinol, Beijing 100029, Peoples R China
2.Peking Univ, Peoples Hosp, Beijing 100871, Peoples R China
3.Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Shanghai 200030, Peoples R China
4.Sun Yat Sen Univ, Hosp 3, Guangzhou 510275, Guangdong, Peoples R China
5.Chinese Peoples Liberat Army Gen Hosp, Beijing, Peoples R China
6.Chinese Med Univ, Affiliated Hosp 1, Liaoling, Peoples R China
7.Nanjing Univ, Sch Med, Affiliated Drum Tower Hosp, Nanjing, Jiangsu, Peoples R China
8.Xinjiang Uygur Autonomous Reg Hosp, Xinjiang, Peoples R China
9.Fujian Prov Hosp, Fujiang, Peoples R China
10.Peking Univ, Hosp 1, Beijing 100871, Peoples R China
11.Harbin Med Univ, Affiliated Hosp 2, Harbin, Heilongjiang, Peoples R China
12.Peking Union Med Coll, Beijing 100021, Peoples R China
13.Tulane Univ, Sch Publ Hlth & Trop Med, New Orleans, LA USA

Recommended Citation:
Yang, Wenying,Xiao, Jianzhong,Yang, Zhaojun,et al. Serum Lipids and Lipoproteins in Chinese Men and Women[J]. CIRCULATION,2012,125(18):2212-2221.
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