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Volume transfer constant (K-trans) maps from dynamic contrast enhanced MRI as potential guidance for MR-guided high intensity focused ultrasound treatment of hypervascular uterine fibroids
Liu, Jing1; Keserci, Bilgin2; Yang, Xuedong1; Wei, Juan3; Rong, Rong1; Zhu, Ying1; Wang, Xiaoying1
关键词MR-guided high intensity focused ultrasound (HIFU) ablation Volume transfer constant (K-trans) map Dynamic contrast enhanced (DCE) Uterine fibroids
刊名MAGNETIC RESONANCE IMAGING
2014-11-01
DOI10.1016/j.mri.2014.05.005
32期:9页:1156-1161
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]LEIOMYOMAS ; SURGERY ; ABLATION ; FEASIBILITY
英文摘要

Higher perfusion of uterine fibroids at baseline is recognized as cause for poor efficacy of MR-guided high intensity focused ultrasound (HIFU) ablation, and higher acoustic power has been suggested for the treatment of high-perfused areas inside uterine fibroids. However, considering the heterogeneously vascular distribution inside the uterine fibroids especially with hyper vascularity, it is not easy to choose the correct therapy acoustic power for every part inside fibroids. In our study, we presented two cases of fibroids with hyper vascularity, to show the differences between them with different outcomes. Selecting higher therapy acoustic powers to ablate high-perfused areas efficiently inside fibroids might help achieving good ablation results. Volume transfer constant (K-trans) maps from dynamic contrast-enhanced (DCE) imaging at baseline helps visualizing perfusion state inside the fibroids and locating areas with higher-perfusion. In addition, with the help of Kt′s maps, appropriate therapy acoustic power could be selected by the result of initial test and therapy sonications at different areas with significantly different perfusion state inside fibroids. (C) 2014 Elsevier Inc. All rights reserved.

语种英语
WOS记录号WOS:000342546700011
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/59361
专题北京大学第一临床医学院_放射治疗科
北京大学第一临床医学院_医学影像科
北京大学第二临床医学院_党委院长办公室
作者单位1.Peking Univ, Hosp 1, Dept Radiol, Beijing, Peoples R China
2.MR Therapy Clin Sci, Seoul 140775, South Korea
3.Philips Res China, Shanghai, Peoples R China
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Liu, Jing,Keserci, Bilgin,Yang, Xuedong,et al. Volume transfer constant (K-trans) maps from dynamic contrast enhanced MRI as potential guidance for MR-guided high intensity focused ultrasound treatment of hypervascular uterine fibroids[J]. MAGNETIC RESONANCE IMAGING,2014,32(9):1156-1161.
APA Liu, Jing.,Keserci, Bilgin.,Yang, Xuedong.,Wei, Juan.,Rong, Rong.,...&Wang, Xiaoying.(2014).Volume transfer constant (K-trans) maps from dynamic contrast enhanced MRI as potential guidance for MR-guided high intensity focused ultrasound treatment of hypervascular uterine fibroids.MAGNETIC RESONANCE IMAGING,32(9),1156-1161.
MLA Liu, Jing,et al."Volume transfer constant (K-trans) maps from dynamic contrast enhanced MRI as potential guidance for MR-guided high intensity focused ultrasound treatment of hypervascular uterine fibroids".MAGNETIC RESONANCE IMAGING 32.9(2014):1156-1161.
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