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The low frequency of reported sexual dysfunction in Asian patients with schizophrenia (2001-2009): low occurrence or ignored side effect?
Xiang, Yu-Tao1,2; Wang, Chuan-Yue2; Si, Tian-Mei3; Lee, Edwin H. M.1; He, Yan-Ling4; Ungvari, Gabor S.5; Chiu, Helen F. K.1; Yang, Shu-Yu6; Chong, Mian-Yoon7,8; Tan, Chay-Hoon9; Kua, Ee-Heok9; Fujii, Senta10; Sim, Kang11; Yong, Michael K. H.11; Trivedi, Jitendra K.12; Chung, Eun-Kee13; Udomratn, Pichet14; Chee, Kok-Yoon15; Sartorius, Norman16; Shinfuku, Naotaka17
关键词antipsychotic drugs schizophrenia sexual dysfunction
刊名HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
2011-06-01
DOI10.1002/hup.1213
26期:4-5页:352-357
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Social Sciences
类目[WOS]Clinical Neurology ; Pharmacology & Pharmacy ; Psychiatry ; Psychology
资助者National Science Foundation ; Beijing Municipal Science and Technology Commission in China ; Chinese University of Hong Kong in Hong Kong ; Institute of Mental Health in Singapore ; Taiwan Bureau of National Health Insurance ; Chang Gung Memorial Hospital ; Taipei City Government in Taiwan ; National Science Foundation ; Beijing Municipal Science and Technology Commission in China ; Chinese University of Hong Kong in Hong Kong ; Institute of Mental Health in Singapore ; Taiwan Bureau of National Health Insurance ; Chang Gung Memorial Hospital ; Taipei City Government in Taiwan
研究领域[WOS]Neurosciences & Neurology ; Pharmacology & Pharmacy ; Psychiatry ; Psychology
关键词[WOS]QUALITY-OF-LIFE ; ANTIPSYCHOTIC TREATMENT ; TARDIVE-DYSKINESIA ; EAST-ASIA ; PREVALENCE ; PRESCRIPTION ; MEDICATIONS ; HALOPERIDOL ; OUTPATIENTS ; RISPERIDONE
英文摘要

Objective The purpose of the study was to evaluate the frequency of reported sexual dysfunction (SD) in schizophrenia and its associations with sociodemographic and clinical variables in selected Asian countries.

Methods A total of 5877 schizophrenia patients in nine Asian countries and territories were examined between 2001 and 2009. The patients′ sociodemographic and clinical characteristics, prescription of psychotropic drugs, and drug-induced side effects were recorded using a standardized protocol and data collection. SD was evaluated as "present" or "absent" according to the clinical judgment of experienced psychiatrists.

Results The frequency of reported SD in the whole sample in women and men was 3.0%, 0.8%, and 4.6%, respectively, with variations across study sites. In the multivariate analyses, male sex, more second-generation antipsychotics, benzodiazepines, and antidepressants were independently associated with higher likelihood of reported SD, whereas negative symptoms had an inverse association with reported SD.

Conclusions The results of this study indicate that SD was seldom recorded as a side effect by Asian psychiatrists while treating patients with schizophrenia. It is unclear whether the low prevalence of reported SD compared with Western data is real or whether the results are being insufficiently recognized. Copyright (C) 2011 John Wiley & Sons, Ltd.

语种英语
所属项目编号30800367 ; 30770776 ; 2008B59 ; 2041454 ; CRC 249/2008 ; DOH92-NH-1025 ; CMRPG83043 ; 97001-62-010
资助者National Science Foundation ; Beijing Municipal Science and Technology Commission in China ; Chinese University of Hong Kong in Hong Kong ; Institute of Mental Health in Singapore ; Taiwan Bureau of National Health Insurance ; Chang Gung Memorial Hospital ; Taipei City Government in Taiwan ; National Science Foundation ; Beijing Municipal Science and Technology Commission in China ; Chinese University of Hong Kong in Hong Kong ; Institute of Mental Health in Singapore ; Taiwan Bureau of National Health Insurance ; Chang Gung Memorial Hospital ; Taipei City Government in Taiwan
WOS记录号WOS:000293964700011
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/59388
专题北京大学精神卫生研究所
作者单位1.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
2.Shanghai Mental Hlth Ctr, Shanghai, Peoples R China
3.Taipei City Hosp, Taipei, Taiwan
4.Kaohsiung Chang Gung Mem Hosp, Kaohsiung, Taiwan
5.Chang Gung Univ, Sch Med, Guishan, Taiwan
6.Natl Univ Singapore, Singapore 117548, Singapore
7.Natl Seoul Hosp, Seoul, South Korea
8.Prince Songkla Univ, Hat Yai, Thailand
9.Assoc Improvement Mental Hlth Programs, Geneva, Switzerland
10.Seinan Gakuin Univ, Sch Human Sci, Fukuoka, Japan
11.HITS, Kobe, Hyogo, Japan
12.Inst Mental Hlth, Buangkok View, Singapore
13.CSM Med Univ UP, Dept Psychiat, Lucknow, Uttar Pradesh, India
14.Chinese Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China
15.Capital Med Univ, Beijing Anding Hosp, Beijing, Peoples R China
16.Univ Notre Dame, Australia Marian Ctr, Perth, WA, Australia
17.Kuala Lumpur Hosp, Tunku Abdul Rahman Inst Neurosci, Dept Psychiat & Mental Hlth, Kuala Lumpur, Malaysia
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GB/T 7714
Xiang, Yu-Tao,Wang, Chuan-Yue,Si, Tian-Mei,et al. The low frequency of reported sexual dysfunction in Asian patients with schizophrenia (2001-2009): low occurrence or ignored side effect?[J]. HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL,2011,26(4-5):352-357.
APA Xiang, Yu-Tao.,Wang, Chuan-Yue.,Si, Tian-Mei.,Lee, Edwin H. M..,He, Yan-Ling.,...&Shinfuku, Naotaka.(2011).The low frequency of reported sexual dysfunction in Asian patients with schizophrenia (2001-2009): low occurrence or ignored side effect?.HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL,26(4-5),352-357.
MLA Xiang, Yu-Tao,et al."The low frequency of reported sexual dysfunction in Asian patients with schizophrenia (2001-2009): low occurrence or ignored side effect?".HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL 26.4-5(2011):352-357.
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