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学科主题: 药学
题名:
Structures and activity of two novel saponins from Albiza julibrissin
作者: Zou, K; Cui, JR; Ran, FX; Wang, B; Zhao, YY; Zhang, RY; Zheng, JH
关键词: Albizia julibrissin ; triterpenoid saponin ; acetamidoglucoside ; julibroside J(22) ; julibroside J(25)
刊名: CHINESE JOURNAL OF ORGANIC CHEMISTRY
发表日期: 2005-06-01
卷: 25, 期:6, 页:654-659
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Organic
研究领域[WOS]: Chemistry
关键词[WOS]: ACACIA-VICTORIAE BENTHAM ; TRITERPENOID SAPONINS ; DIASTEREOISOMERIC SAPONINS ; AVICINS ; IDENTIFICATION ; FAMILY
英文摘要:

Two triterpene saponins acylated with monoterpenoid were isolated from the stem barks of Albizia julibrissin. Their structures were identified as 3-O-[β-D-xylopyranosyl-(1→ 2)-α-L-arabinopyranosyl(1→ 6)-6-β-D-glucopyranosyl]-21-O-[(6S)-2-trans-2-hydroxymethyl-6-methyl-6-O-β-D-quinovopyranosyl- 2,7-octadienoyl]-acacic acid-28-O-β-D-glucopyranosyl-(1→ 3)-[α-2-arabinofuranosyl-(1→ 4)-α-L-rhomnopyranosyl-(1→ 2)-β-D-glucopyranosylester (1) and 3-O-[β-D-xylopyranosyl-(1→ 2)-α-L-arabinopyranosyl(1→ 6)-β-D-2-deoxy-2-acetamidoglucopyranosyl]-21-O-[(6S)-2-trans-2-hyqoxymethyl-6-methyl-6-O-β-D- quinovopyranosyl-2,7-octadienoyl]-acacic acid-28-O-β-D-glucopyranosyl-(1→ 3)-[α-L-arabinofuranosyl(1→ 4)]-α-L-rhamnopyranosyl-(1→ 2)-β-D-glucopyranosyl ester (2) based on chemical and spectroscopic methods, respectively, named as Julibrosides J(25) and J(22). Julibrosides J(25) and J(22) showed marked activities against four kinds of cancer cell lines in a concentration of 100 μ g/mL assayed by SRB method.

语种: 中文
WOS记录号: WOS:000229524700006
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59396
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Peking Univ, Sch Pharmaceut Sci, Beijing 100083, Peoples R China
2.China Tree Gorges Univ, Coll Chem & Life Sci, Yichang 443000, Peoples R China
3.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China

Recommended Citation:
Zou, K,Cui, JR,Ran, FX,et al. Structures and activity of two novel saponins from Albiza julibrissin[J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY,2005,25(6):654-659.
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