北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第二临床医学院  > 胸外科  > 期刊论文
学科主题: 临床医学
题名:
Diagnostic value of endobronchial ultrasound-guided transbronchial needle aspiration in intrapulmonary lesions
作者: Zhao Hui; Xie Zhen; Zhou Zu-li; Sui Xi-zhao; Wang Jun
关键词: endobronchial ultrasound ; transbronchial needle aspiration ; lung cancer ; diagnosis
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2013-11-20
DOI: 10.3760/cma.j.issn.0366-6999.20131560
卷: 126, 期:22, 页:4312-4315
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: LUNG-CANCER ; PULMONARY NODULES ; RANDOMIZED-TRIAL ; BIOPSY ; PNEUMOTHORAX ; IMPLANTATION ; CARCINOMA
英文摘要:

Background Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is considered to have high value in the staging of mediastinal lymph nodes in lung cancer. The current study was conducted to investigate the diagnostic value of EBUS-TBNA in intrapulmonary lesions located near the central airway.

Methods From September 2009 to March 2013, 66 patients with pulmonary masses located close to the central airways suspected to be lung cancer were accessed by EBUS-TBNA. Conventional bronchoscopic biopsy before EBUS-TBNA was nondiagnostic in all cases. If EBUS-TBNA did not result in a formal pathological diagnosis of malignancy, patients were subsequently referred for a surgical procedure.

Results Among the 66 cases, 59 were confirmed as pulmonary malignancies by EBUS-TBNA, of which 48 cases were non-small cell lung cancer, nine were small cell lung cancer, and two were metastatic lung tumors. No evidence of malignancy was found by biopsy and histopathological examination in the other seven cases. Thoracoscopy or thoracotomy was subsequently undergone for them. Postoperative pathological examinations confirmed three cases of squamous cell carcinoma of the lung, one case of lymphoma, two cases of sclerosing hemangioma, and one case of pulmonary tuberculoma. The definitive diagnosis rate of EBUS-TBNA for intrapulmonary lesions near the central airway was 89.4%. The sensitivity, specificity, and accuracy of EBUS-TBNA in distinguishing benign from malignant intrapulmonary lesions were 93.7%, 100.0%, and 93.9%, respectively. The positive and negative predictive values were 100.0% and 42.9%, respectively. The EBUS-TBNA procedures were well-tolerated by all patients. No associated complications were observed.

Conclusions For intrapulmonary lesions near the central airway highly suspected of cancer, EBUS-TBNA has satisfactory diagnostic value. However, the negative predictive value of this technique is low, so negative results obtained by EBUS-TBNA should be confirmed by other methods.

语种: 英语
WOS记录号: WOS:000327916600024
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59665
Appears in Collections:北京大学第二临床医学院_胸外科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, Peoples Hosp, Dept Thorac Surg, Beijing 100044, Peoples R China

Recommended Citation:
Zhao Hui,Xie Zhen,Zhou Zu-li,et al. Diagnostic value of endobronchial ultrasound-guided transbronchial needle aspiration in intrapulmonary lesions[J]. CHINESE MEDICAL JOURNAL,2013,126(22):4312-4315.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Zhao Hui]'s Articles
[Xie Zhen]'s Articles
[Zhou Zu-li]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Zhao Hui]‘s Articles
[Xie Zhen]‘s Articles
[Zhou Zu-li]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace