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学科主题: 临床医学
题名:
Treatment, Monitoring, and Economic Outcomes of Venous Thromboembolism Among Hospitalized Patients in China
作者: Wu, Eric Q.1; Xie, Jipan2; Wu, Chun3; Du, Ella Xiaoyan1; Li, Nanxin1; Tan, Ruoding1; Liu, Yuanli4
刊名: PHARMACOECONOMICS
发表日期: 2014-03-01
DOI: 10.1007/s40273-014-0131-4
卷: 32, 期:3, 页:305-313
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Social Sciences ; Science & Technology
类目[WOS]: Economics ; Health Care Sciences & Services ; Health Policy & Services ; Pharmacology & Pharmacy
研究领域[WOS]: Business & Economics ; Health Care Sciences & Services ; Pharmacology & Pharmacy
关键词[WOS]: ORAL ANTICOAGULANT-THERAPY ; PREVENTION ; THROMBOSIS
英文摘要:

The prevalence of venous thromboembolism (VTE) has been increasing in China. However, the treatment pattern and economic burden of these patients have not been well-understood.

The objective of this study was to examine the patient characteristics, treatment pattern, anticoagulant monitoring, and economic burden of VTE among hospitalized patients in China.

Hospitalizations with a diagnosis of VTE [including deep vein thrombosis (DVT) or pulmonary embolism (PE)] between 1 January 2010 and 30 June 2013 were included. Descriptive analysis was conducted for patients′ characteristics, anticoagulant treatment, international normalized ratio (INR) monitoring, and hospitalization cost [in 2013 Chinese yuan (Y) and US dollars (US$)]. Multivariate regressions were performed to assess factors associated with oral anticoagulant use and total costs of inpatient care.

A total of 1,047 VTE-related hospitalizations were selected. The sample had a mean age of 62.4 years, with 45.9 % female. About 46.3 % of hospitalizations used heparin only, 35.0 % used warfarin, 0.8 % used rivaroxaban, and 18.0 % did not use anticoagulants. Among hospitalizations where warfarin was used, 90.8 % received at least one INR test and only 30 % had the last INR within the target therapeutic range (2-3) before discharge. The mean (standard deviation) total cost per hospitalization was Y29,114 (43,772) [US$4,757 (7,152)]. PE, VTE as primary diagnosis, female, insurance coverage, anticoagulant treatment, co-morbidities, admission condition, and surgical procedure were significantly associated with inpatient costs.

Conventional anticoagulants were most commonly used in the study sample. Under-monitoring and suboptimal care may be an issue for patients treated with warfarin. The average total inpatient cost of VTE-related hospitalizations is high.

语种: 英语
项目资助者: Analysis Group, Inc.
WOS记录号: WOS:000332490100008
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59677
Appears in Collections:北京大学深圳医院_心血管内科_期刊论文

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作者单位: 1.Anal Grp Inc, Boston, MA 02199 USA
2.Anal Grp Inc, New York, NY USA
3.Peking Univ, Shenzhen Hosp, Dept Cardiol, Shenzhen, Guangdong, Peoples R China
4.Harvard Univ, Sch Publ Hlth, Dept Global Hlth & Populat, Boston, MA 02115 USA

Recommended Citation:
Wu, Eric Q.,Xie, Jipan,Wu, Chun,et al. Treatment, Monitoring, and Economic Outcomes of Venous Thromboembolism Among Hospitalized Patients in China[J]. PHARMACOECONOMICS,2014,32(3):305-313.
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