IR@PKUHSC  > 北京大学深圳医院  > 心血管内科
学科主题临床医学
Treatment, Monitoring, and Economic Outcomes of Venous Thromboembolism Among Hospitalized Patients in China
Wu, Eric Q.1; Xie, Jipan2; Wu, Chun3; Du, Ella Xiaoyan1; Li, Nanxin1; Tan, Ruoding1; Liu, Yuanli4
刊名PHARMACOECONOMICS
2014-03-01
DOI10.1007/s40273-014-0131-4
32期:3页:305-313
收录类别SCI ; SSCI
文章类型Article
WOS标题词Social Sciences ; Science & Technology
类目[WOS]Economics ; Health Care Sciences & Services ; Health Policy & Services ; Pharmacology & Pharmacy
研究领域[WOS]Business & Economics ; Health Care Sciences & Services ; Pharmacology & Pharmacy
关键词[WOS]ORAL ANTICOAGULANT-THERAPY ; PREVENTION ; THROMBOSIS
英文摘要

The prevalence of venous thromboembolism (VTE) has been increasing in China. However, the treatment pattern and economic burden of these patients have not been well-understood.

The objective of this study was to examine the patient characteristics, treatment pattern, anticoagulant monitoring, and economic burden of VTE among hospitalized patients in China.

Hospitalizations with a diagnosis of VTE [including deep vein thrombosis (DVT) or pulmonary embolism (PE)] between 1 January 2010 and 30 June 2013 were included. Descriptive analysis was conducted for patients′ characteristics, anticoagulant treatment, international normalized ratio (INR) monitoring, and hospitalization cost [in 2013 Chinese yuan (Y) and US dollars (US$)]. Multivariate regressions were performed to assess factors associated with oral anticoagulant use and total costs of inpatient care.

A total of 1,047 VTE-related hospitalizations were selected. The sample had a mean age of 62.4 years, with 45.9 % female. About 46.3 % of hospitalizations used heparin only, 35.0 % used warfarin, 0.8 % used rivaroxaban, and 18.0 % did not use anticoagulants. Among hospitalizations where warfarin was used, 90.8 % received at least one INR test and only 30 % had the last INR within the target therapeutic range (2-3) before discharge. The mean (standard deviation) total cost per hospitalization was Y29,114 (43,772) [US$4,757 (7,152)]. PE, VTE as primary diagnosis, female, insurance coverage, anticoagulant treatment, co-morbidities, admission condition, and surgical procedure were significantly associated with inpatient costs.

Conventional anticoagulants were most commonly used in the study sample. Under-monitoring and suboptimal care may be an issue for patients treated with warfarin. The average total inpatient cost of VTE-related hospitalizations is high.

语种英语
WOS记录号WOS:000332490100008
资助机构Analysis Group, Inc.
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/59677
专题北京大学深圳医院_心血管内科
作者单位1.Anal Grp Inc, Boston, MA 02199 USA
2.Anal Grp Inc, New York, NY USA
3.Peking Univ, Shenzhen Hosp, Dept Cardiol, Shenzhen, Guangdong, Peoples R China
4.Harvard Univ, Sch Publ Hlth, Dept Global Hlth & Populat, Boston, MA 02115 USA
推荐引用方式
GB/T 7714
Wu, Eric Q.,Xie, Jipan,Wu, Chun,et al. Treatment, Monitoring, and Economic Outcomes of Venous Thromboembolism Among Hospitalized Patients in China[J]. PHARMACOECONOMICS,2014,32(3):305-313.
APA Wu, Eric Q..,Xie, Jipan.,Wu, Chun.,Du, Ella Xiaoyan.,Li, Nanxin.,...&Liu, Yuanli.(2014).Treatment, Monitoring, and Economic Outcomes of Venous Thromboembolism Among Hospitalized Patients in China.PHARMACOECONOMICS,32(3),305-313.
MLA Wu, Eric Q.,et al."Treatment, Monitoring, and Economic Outcomes of Venous Thromboembolism Among Hospitalized Patients in China".PHARMACOECONOMICS 32.3(2014):305-313.
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