IR@PKUHSC  > 北京大学第一临床医学院
学科主题临床医学
A case of Francisella tularensis subspecies holarctica in China
Wang, Yan-Hua1; Qiao, Fu-Yu2; Cao, Ju3; Peng, Yao1; Li, Hang4; Xia, Lian-Xu1; Hai, Rong1
关键词Francisella tularensis subsp holarctica Tularemia Phylogeography SNP canSNP INDEL MLVA China
刊名TICKS AND TICK-BORNE DISEASES
2015
DOI10.1016/j.ttbdis.2015.07.007
6期:6页:802-804
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Infectious Diseases ; Microbiology ; Parasitology
资助者National Natural Science Foundation of China ; China Mega-Project for Infectious Disease ; National Natural Science Foundation of China ; China Mega-Project for Infectious Disease
研究领域[WOS]Infectious Diseases ; Microbiology ; Parasitology
关键词[WOS]TULAREMIA
英文摘要

We report a highly unusual case of ulceroglandular tularemia in Beijing, China. The serological texting, and sequencing of three specific genes by PCR analysis, suggested that this case was infected by Francisella tularensis. Next, using 15 canonical single-nucleotide polymorphisms and insertion-deletion markers (SNPs-INDELs) and five variable-number tandem repeat loci (VNTRs), this case was assigned to a known clade from Russia, and not to the four clades that were previously identified, including previous Chinese isolates. The case that is reported herein provides evidence of type B tularemia in Beijing, and it demonstrates unprecedented levels of diversity of the Chinese variant of F. tularensis. (C) 2015 Elsevier GmbH. All rights reserved.

语种英语
所属项目编号81473032 ; 2013ZX10004-101 ; 2012ZX10004219
资助者National Natural Science Foundation of China ; China Mega-Project for Infectious Disease ; National Natural Science Foundation of China ; China Mega-Project for Infectious Disease
WOS记录号WOS:000362143800017
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/59697
专题北京大学第一临床医学院
作者单位1.Collaborat Innovat Ctr Diag & Treatment Infect Di, Dept Plague, Natl Inst Communicable Dis Control & Prevent, State Key Lab Infect Dis Prevent & Control, Beijing, Peoples R China
2.Xicheng Dist Ctr Dis Prevent & Control, Beijing, Peoples R China
3.Peking Univ, Hosp 1, Beijing 100871, Peoples R China
4.Beijing Genom Inst Shenzhen, Shenzhen, Peoples R China
推荐引用方式
GB/T 7714
Wang, Yan-Hua,Qiao, Fu-Yu,Cao, Ju,et al. A case of Francisella tularensis subspecies holarctica in China[J]. TICKS AND TICK-BORNE DISEASES,2015,6(6):802-804.
APA Wang, Yan-Hua.,Qiao, Fu-Yu.,Cao, Ju.,Peng, Yao.,Li, Hang.,...&Hai, Rong.(2015).A case of Francisella tularensis subspecies holarctica in China.TICKS AND TICK-BORNE DISEASES,6(6),802-804.
MLA Wang, Yan-Hua,et al."A case of Francisella tularensis subspecies holarctica in China".TICKS AND TICK-BORNE DISEASES 6.6(2015):802-804.
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