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学科主题: 临床医学
题名:
A case of Francisella tularensis subspecies holarctica in China
作者: Wang, Yan-Hua1; Qiao, Fu-Yu2; Cao, Ju3; Peng, Yao1; Li, Hang4; Xia, Lian-Xu1; Hai, Rong1
关键词: Francisella tularensis subsp holarctica ; Tularemia ; Phylogeography ; SNP ; canSNP ; INDEL ; MLVA ; China
刊名: TICKS AND TICK-BORNE DISEASES
发表日期: 2015
DOI: 10.1016/j.ttbdis.2015.07.007
卷: 6, 期:6, 页:802-804
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Infectious Diseases ; Microbiology ; Parasitology
研究领域[WOS]: Infectious Diseases ; Microbiology ; Parasitology
关键词[WOS]: TULAREMIA
英文摘要:

We report a highly unusual case of ulceroglandular tularemia in Beijing, China. The serological texting, and sequencing of three specific genes by PCR analysis, suggested that this case was infected by Francisella tularensis. Next, using 15 canonical single-nucleotide polymorphisms and insertion-deletion markers (SNPs-INDELs) and five variable-number tandem repeat loci (VNTRs), this case was assigned to a known clade from Russia, and not to the four clades that were previously identified, including previous Chinese isolates. The case that is reported herein provides evidence of type B tularemia in Beijing, and it demonstrates unprecedented levels of diversity of the Chinese variant of F. tularensis. (C) 2015 Elsevier GmbH. All rights reserved.

语种: 英语
所属项目编号: 81473032 ; 2013ZX10004-101 ; 2012ZX10004219
项目资助者: National Natural Science Foundation of China ; China Mega-Project for Infectious Disease
WOS记录号: WOS:000362143800017
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59697
Appears in Collections:北京大学第一临床医学院_期刊论文

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作者单位: 1.Collaborat Innovat Ctr Diag & Treatment Infect Di, Dept Plague, Natl Inst Communicable Dis Control & Prevent, State Key Lab Infect Dis Prevent & Control, Beijing, Peoples R China
2.Xicheng Dist Ctr Dis Prevent & Control, Beijing, Peoples R China
3.Peking Univ, Hosp 1, Beijing 100871, Peoples R China
4.Beijing Genom Inst Shenzhen, Shenzhen, Peoples R China

Recommended Citation:
Wang, Yan-Hua,Qiao, Fu-Yu,Cao, Ju,et al. A case of Francisella tularensis subspecies holarctica in China[J]. TICKS AND TICK-BORNE DISEASES,2015,6(6):802-804.
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