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学科主题: 临床医学
题名:
Biomechanical effects of cervical arthroplasty with U-shaped disc implant on segmental range of motion and loading of surrounding soft tissue
作者: Mo, Zhong Jun1,2; Bin Zhao, Yan3; Wang, Li Zhen1; Sun, Yu3; Zhang, Ming2; Fan, Yu Bo1
关键词: Cervical disc arthroplasty ; U-shaped implant ; Finite element method ; Range of motion ; Intradiscal pressure ; Ligament strain
刊名: EUROPEAN SPINE JOURNAL
发表日期: 2014-03-01
DOI: 10.1007/s00586-013-3070-4
卷: 23, 期:3, 页:613-621
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology ; Orthopedics
研究领域[WOS]: Neurosciences & Neurology ; Orthopedics
关键词[WOS]: INTRADISCAL PRESSURE ; SPINE ; FUSION ; FLEXIBILITY ; REPLACEMENT ; DISKECTOMY ; MODEL
英文摘要:

Various design concepts have been adopted in cervical disc prostheses, including sliding articulation and standalone configuration. This study aimed to evaluate the biomechanical effects of the standalone U-shaped configuration on the cervical spine.

Based on an intact finite element model of C3-C7, a standalone U-shaped implant (DCI) was installed at C5-C6 and compared with a sliding articulation design (Prodisc-C) and an anterior fusion system. The range of motion (ROM), adjacent intradiscal pressure (IDP) and capsular ligament strain were calculated under different spinal motions.

Compared to the intact configuration, the ROM at C5-C6 was reduced by 90 % after fusion, but increased by 70 % in the Prodisc-C model, while the maximum percentage change in the DCI model was 30 % decrease. At the adjacent segments, up to 32 % increase in ROM happened after fusion, while up to 34 % decrease occurred in Prodisc-C model and 17 % decrease in DCI model. The IDP increased by 11.6 % after fusion, but decreased by 5.6 and 6.3 % in the DCI and Prodisc-C model, respectively. The capsular ligament strain increased by 147 % in Prodisc-C and by 13 % in the DCI model. The DCI implant exhibited a high stress distribution.

Spinal fusion resulted in compensatory increase of ROM at the adjacent sites, thereby elevating the IDP. Prodisc-C resulted in hyper-mobility at the operative site that led to an increase of ligament force and strain. The U-shaped implant could maintain the spinal kinematics and impose minimum influence on the adjacent soft tissues, despite the standalone configuration encountering the disadvantages of high stress distribution.

语种: 英语
所属项目编号: 10925208 ; 11120101001 ; 11202017 ; 11272273 ; 81271666 ; B13003 ; 2012BAI18B05 ; 2012BAI18B07 ; G-UA40
项目资助者: National Natural Science Foundation of China ; 111 Project ; National Science &amp ; Technology Pillar Program ; Hong Kong Polytechnic university Research Grant
WOS记录号: WOS:000332604600020
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59711
Appears in Collections:北京大学第三临床医学院_骨科_期刊论文

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作者单位: 1.Beihang Univ, Sch Biol Sci & Med Engn, Minist Sci & Technol, Int Joint Res Ctr Aerosp Biotechnol & Med Engn, Beijing 100191, Peoples R China
2.Hong Kong Polytech Univ, Interdisciplinary Div Biomed Engn, Hong Kong, Hong Kong, Peoples R China
3.Peking Univ, Hosp 3, Dept Orthoped Surg, Beijing 100191, Peoples R China

Recommended Citation:
Mo, Zhong Jun,Bin Zhao, Yan,Wang, Li Zhen,et al. Biomechanical effects of cervical arthroplasty with U-shaped disc implant on segmental range of motion and loading of surrounding soft tissue[J]. EUROPEAN SPINE JOURNAL,2014,23(3):613-621.
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