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The individualized choice of embryo transfer timing for patients with elevated serum progesterone level on the HCG day in IVF/ICSI cycles: a prospective randomized clinical study
Yang, Shuo; Pang, Tianshu; Li, Rong; Yang, Rui; Zhen, Xiumei; Chen, Xinna; Wang, Haiyan; Ma, Caihong; Liu, Ping; Qiao, Jie
关键词Blastocyst elevated progesterone frozen HCG administration in vitro fertilization
刊名GYNECOLOGICAL ENDOCRINOLOGY
2015-05-01
DOI10.3109/09513590.2014.995620
31期:5页:355-358
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Endocrinology & Metabolism ; Obstetrics & Gynecology
资助者National Natural Science Foundation of China ; Beijing Municipal Natural Science Foundation ; National Natural Science Foundation of China ; Beijing Municipal Natural Science Foundation
研究领域[WOS]Endocrinology & Metabolism ; Obstetrics & Gynecology
关键词[WOS]HUMAN CHORIONIC-GONADOTROPIN ; IN-VITRO FERTILIZATION ; INTRACYTOPLASMIC SPERM INJECTION ; OVARIAN STIMULATION ; GNRH AGONIST ; PREGNANCY ; FRESH ; IVF ; ANTAGONIST ; STRATEGY
英文摘要

This study analyzed the clinical outcomes of patients with elevated progesterone level on the HCG day in IVF/ICSI cycles, with different timing of embryo transfer. A total of 123 patients were involved in this prospective randomized clinical study. Group 1: blastocyst transfer group, 38 cases; Group 2: frozen thawed embryo transfer group (first FET cycle), 42 cases; Group 3: fresh embryo transfer group, 43 cases. The basal FSH level was comparable among three groups (6.7 +/- 3 versus 7.0 +/- 2 versus 6.9 +/- 2.4, p = 0.897). The clinical pregnancy rate was highest in group 2, lowest in group 3, with significantly difference (31.6% versus 38.1% versus 13.9%, p = 0.037). The implantation rate and live birth rate were still lowest in group 3 (21.9% versus 19.8% versus 6.7%, p = 0.016 and 18.4% versus 31% versus 11.6%, p = 0.081). In conclusion, the elevated progesterone level will affect clinical pregnancy rate in fresh embryo transfer cycles. We suggest frozen-thawed embryo transfer for these patients. However, for those patients who expressed the wish to have fresh embryo transfer, they should be suggested fresh blastocyst transfer, if they have more than five good quality embryos.

语种英语
所属项目编号30825038 ; 7142166
资助者National Natural Science Foundation of China ; Beijing Municipal Natural Science Foundation ; National Natural Science Foundation of China ; Beijing Municipal Natural Science Foundation
WOS记录号WOS:000358972300004
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/59717
专题北京大学第三临床医学院_生殖医学中心
作者单位Peking Univ, Hosp 3, Reprod Med Ctr, Dept Obstet & Gynecol, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Yang, Shuo,Pang, Tianshu,Li, Rong,et al. The individualized choice of embryo transfer timing for patients with elevated serum progesterone level on the HCG day in IVF/ICSI cycles: a prospective randomized clinical study[J]. GYNECOLOGICAL ENDOCRINOLOGY,2015,31(5):355-358.
APA Yang, Shuo.,Pang, Tianshu.,Li, Rong.,Yang, Rui.,Zhen, Xiumei.,...&Qiao, Jie.(2015).The individualized choice of embryo transfer timing for patients with elevated serum progesterone level on the HCG day in IVF/ICSI cycles: a prospective randomized clinical study.GYNECOLOGICAL ENDOCRINOLOGY,31(5),355-358.
MLA Yang, Shuo,et al."The individualized choice of embryo transfer timing for patients with elevated serum progesterone level on the HCG day in IVF/ICSI cycles: a prospective randomized clinical study".GYNECOLOGICAL ENDOCRINOLOGY 31.5(2015):355-358.
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