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IR@PKUHSC  > 北京大学第二临床医学院  > 血液科  > 期刊论文
学科主题: 临床医学
题名:
Identification of a novel HLA-DRB1 allele (HLA-DRB1*111902*)
作者: Li, D; Gao, HF; Liu, X; Liu, X; Jiang, D; Li, Z; Liu, YH; Jiang, YZ; Li, L; Lan, GX; Zhao, CZ; Guo, T; Cai, B; Wang, D; Sun, GY; Zhang, D; Lu, DP
关键词: chip-based sequence-specific digonucleotide technique ; HLA-DRB1*111902
刊名: TISSUE ANTIGENS
发表日期: 2005-07-01
DOI: 10.1111/j.1399-0039.2005.00404.x
卷: 66, 期:1, 页:67-68
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Cell Biology ; Immunology ; Pathology
研究领域[WOS]: Cell Biology ; Immunology ; Pathology
英文摘要:

In this paper, we report a new HLA-DRB1 allele identified in a male acute myeloid leukaemia Chinese patient. This sample was initially typed as DRB1*11XX using commercial polymerase chain reaction-sequence-specific primers kit. When it was typed using a chip-based sequence-specific oligonucleotide technique, a novel hybridization pattern that does not match any known alleles was observed. Through sequencing, we have identified this allele as a new HLA-DRB1 allele, which was later named HLA-DRB1*111902 by the WHO Nomenclature Committee. The sequence of this new allele differs from DRB1*111901 by one nucleotide (from G to C) at 203nt of exon 2 but does not cause any amino acid substitution.

语种: 英语
WOS记录号: WOS:000230430700014
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59721
Appears in Collections:北京大学第二临床医学院_血液科_期刊论文

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作者单位: 1.CapitalBio Corp, Beijing, Peoples R China
2.Beijing Biochip Technol, Natl Engn Res Ctr, Beijing, Peoples R China
3.Peking Univ, Inst Hematol, Beijing 100044, Peoples R China
4.Peking Univ, Peoples Hosp, Beijing 100044, Peoples R China

Recommended Citation:
Li, D,Gao, HF,Liu, X,et al. Identification of a novel HLA-DRB1 allele (HLA-DRB1*111902*)[J]. TISSUE ANTIGENS,2005,66(1):67-68.
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