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学科主题: 临床医学
题名:
Modular hemipelvic endoprosthesis reconstruction-Experience in 100 patients with mid-term follow-up results
作者: Ji, T.; Guo, W.; Yang, R. L.; Tang, X. D.; Wang, Y. F.
关键词: Endoprosthesis ; Pelvic tumor ; Limb salvage ; Reconstruction ; Sarcoma
刊名: EJSO
发表日期: 2013
DOI: 10.1016/j.ejso.2012.10.002
卷: 39, 期:1, 页:53-60
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Oncology ; Surgery
研究领域[WOS]: Oncology ; Surgery
关键词[WOS]: LIMB SALVAGE ; OPERATIVE TREATMENT ; SURGICAL-TREATMENT ; SADDLE PROSTHESIS ; BONE-TUMORS ; RESECTION ; PELVIS ; SURGERY ; COMPLICATIONS ; REPLACEMENT
英文摘要:

Introduction: Pelvic endoprostheses are becoming more commonly used in recent years. In 2007, we reported the early results of modular hemipelvic endoprosthesis. In order to provide longer follow-up results, we conducted the current study.

Objective: To explore overall survival, local recurrence rate, metastasis rate, function score and survivorship of the prosthesis and related complications.

Methods: We retrospectively reviewed one hundred consecutive patients who received reconstruction with modular hemipelvic endoprostheses from June 2001 to March 2010. The living patients were followed for an average of 52.9 (range, 24-103) months. There were 85 primary tumors and 15 isolated metastases.

Results: At the time of last follow-up, fifty-eight patients were alive with no evidence of disease and thirty-six patients died of disease. Twenty patients experienced a local recurrence and twenty-eight patients developed distant metastasis. Patients with wide surgical margins had a significantly lower local recurrence rate than those with inadequate margins (p = 0.03). The mean MSTS (Musculoskeletal Tumor Society) 93 score was 57.2% (range, 16.7-86.7%). The mean Karnofsky Performance Score (KPS) was 64.4 (range, 30-90). Postoperative complications occurred in 45% of the patients. Wound healing disturbance (18%) and deep infection (15%) were the most predominant. Less frequent complications included dislocation, which occurred in nine patients and mechanical complications including 5 breakages and 2 aseptic loosening.

Conclusion: The modular hemipelvic endoprosthesis can provide a versatile reconstruction option for a variety of pelvic defects with an acceptable rate of complication. Wide margins whenever possible should be the goal for these complex patients. (c) 2012 Elsevier Ltd. All rights reserved.

语种: 英语
WOS记录号: WOS:000315421700009
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59778
Appears in Collections:北京大学第二临床医学院_骨肿瘤科_期刊论文

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作者单位: Peking Univ, Peoples Hosp, Musculoskeletal Tumor Ctr, Beijing 100044, Peoples R China

Recommended Citation:
Ji, T.,Guo, W.,Yang, R. L.,et al. Modular hemipelvic endoprosthesis reconstruction-Experience in 100 patients with mid-term follow-up results[J]. EJSO,2013,39(1):53-60.
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