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学科主题临床医学
Modular hemipelvic endoprosthesis reconstruction-Experience in 100 patients with mid-term follow-up results
Ji, T.; Guo, W.; Yang, R. L.; Tang, X. D.; Wang, Y. F.
关键词Endoprosthesis Pelvic tumor Limb salvage Reconstruction Sarcoma
刊名EJSO
2013
DOI10.1016/j.ejso.2012.10.002
39期:1页:53-60
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Oncology ; Surgery
研究领域[WOS]Oncology ; Surgery
关键词[WOS]LIMB SALVAGE ; OPERATIVE TREATMENT ; SURGICAL-TREATMENT ; SADDLE PROSTHESIS ; BONE-TUMORS ; RESECTION ; PELVIS ; SURGERY ; COMPLICATIONS ; REPLACEMENT
英文摘要

Introduction: Pelvic endoprostheses are becoming more commonly used in recent years. In 2007, we reported the early results of modular hemipelvic endoprosthesis. In order to provide longer follow-up results, we conducted the current study.

Objective: To explore overall survival, local recurrence rate, metastasis rate, function score and survivorship of the prosthesis and related complications.

Methods: We retrospectively reviewed one hundred consecutive patients who received reconstruction with modular hemipelvic endoprostheses from June 2001 to March 2010. The living patients were followed for an average of 52.9 (range, 24-103) months. There were 85 primary tumors and 15 isolated metastases.

Results: At the time of last follow-up, fifty-eight patients were alive with no evidence of disease and thirty-six patients died of disease. Twenty patients experienced a local recurrence and twenty-eight patients developed distant metastasis. Patients with wide surgical margins had a significantly lower local recurrence rate than those with inadequate margins (p = 0.03). The mean MSTS (Musculoskeletal Tumor Society) 93 score was 57.2% (range, 16.7-86.7%). The mean Karnofsky Performance Score (KPS) was 64.4 (range, 30-90). Postoperative complications occurred in 45% of the patients. Wound healing disturbance (18%) and deep infection (15%) were the most predominant. Less frequent complications included dislocation, which occurred in nine patients and mechanical complications including 5 breakages and 2 aseptic loosening.

Conclusion: The modular hemipelvic endoprosthesis can provide a versatile reconstruction option for a variety of pelvic defects with an acceptable rate of complication. Wide margins whenever possible should be the goal for these complex patients. (c) 2012 Elsevier Ltd. All rights reserved.

语种英语
WOS记录号WOS:000315421700009
引用统计
被引频次:17[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/59778
专题北京大学第二临床医学院_骨肿瘤科
北京大学药学院_天然药物与仿生药物国家重点实验室
作者单位Peking Univ, Peoples Hosp, Musculoskeletal Tumor Ctr, Beijing 100044, Peoples R China
推荐引用方式
GB/T 7714
Ji, T.,Guo, W.,Yang, R. L.,et al. Modular hemipelvic endoprosthesis reconstruction-Experience in 100 patients with mid-term follow-up results[J]. EJSO,2013,39(1):53-60.
APA Ji, T.,Guo, W.,Yang, R. L.,Tang, X. D.,&Wang, Y. F..(2013).Modular hemipelvic endoprosthesis reconstruction-Experience in 100 patients with mid-term follow-up results.EJSO,39(1),53-60.
MLA Ji, T.,et al."Modular hemipelvic endoprosthesis reconstruction-Experience in 100 patients with mid-term follow-up results".EJSO 39.1(2013):53-60.
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