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Fine particulate matter, temperature, and lung function in healthy adults: Findings from the HVNR study
Wu, Shaowei1; Deng, Furong1; Hao, Yu1; Wang, Xin1; Zheng, Chanjuan1; Lv, Haibo1; Lu, Xiuling1; Wei, Hongying1; Huang, Jing1; Qin, Yu1; Shima, Masayuki2; Guo, Xinbiao1
关键词Air pollution Lung function Particulate matter Peak expiratory flow Temperature
刊名CHEMOSPHERE
2014-08-01
DOI10.1016/j.chemosphere.2014.01.032
108页:168-174
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Environmental Sciences
研究领域[WOS]Environmental Sciences & Ecology
关键词[WOS]HEART-RATE-VARIABILITY ; PEAK EXPIRATORY FLOW ; AIR-POLLUTION ; CHEMICAL-CONSTITUENTS ; EXPOSURE ; PANEL ; ASSOCIATION ; MORTALITY ; DISEASE ; ASTHMA
英文摘要

Both ambient particulate air pollution and temperature alterations have been associated with adverse human health effects, but the interactive effect of ambient particulate and temperature on human health remains uncertain. The present study investigated the effects of ambient particulate matter with an aerodynamic diameter <= 2.5 mu m (PM2.5) and temperature on human lung function simultaneously in a panel of 21 healthy university students from the Healthy Volunteer Natural Relocation (HVNR) study in the context of suburban/urban air pollution in Beijing, China. Each study subject used an electronic diary meter to record peak expiratory flow (PEF) and forced expiratory volume in 1 s (FEV1) twice a day for 6 months in three periods before and after relocating from a suburban area to an urban area with changing ambient PM2.5 and temperature levels in Beijing. Hourly-averaged environmental data were obtained from central air-monitoring sites. Exposure effects were estimated using generalized linear mixed models controlling for potential confounders. Study subjects provided 6494 daily measurements on PEF and 6460 daily measurements on FEV1 over the study. PM2.5 was associated with reductions in evening PEF and morning/evening FEV1 whereas temperature was associated with reductions in morning PEF. The estimated PM2.5 effects on evening PEF and morning/evening FEV1 in the presence of high temperature were generally stronger than those in the presence of low temperature, and the estimated temperature effects on morning/evening PEF and morning FEV1 in the presence of high PM2.5 were also generally stronger than those in the presence of low PM2.5. For example, there were a 2.47% (95% confidence interval: -4.24, -0.69) reduction and a 0.78% (95% confidence interval: -1.59,0.03) reduction in evening PEF associated with an interquartile range increase (78.7 mu g/m(3)) in PM2.5 at 4-d moving average in the presence of high temperature (>= 21.6 degrees C) and low temperature (<21.6 degrees C), respectively. Our findings suggest that ambient particulate and temperature may interact synergistically to cause adverse respiratory health effects. (C) 2014 Elsevier Ltd. All rights reserved.

语种英语
WOS记录号WOS:000337881600022
项目编号81072267 ; 2006BAI19B06 ; 2012AA062804
资助机构National Natural Science Foundation of China ; National Key Technologies R&amp ; D Program of China ; National High Technology Research and Development Program of China ; Ministry of Education of the People&prime ; s Republic of China
引用统计
被引频次:24[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/59785
专题北京大学公共卫生学院
北京大学公共卫生学院_劳动卫生与环境卫生学系
北京大学公共卫生学院_公共卫生学院
作者单位1.Peking Univ, Sch Publ Hlth, Dept Occupat & Environm Hlth Sci, Beijing 100191, Peoples R China
2.Hyogo Coll Med, Dept Publ Hlth, Nishinomiya, Hyogo, Japan
推荐引用方式
GB/T 7714
Wu, Shaowei,Deng, Furong,Hao, Yu,et al. Fine particulate matter, temperature, and lung function in healthy adults: Findings from the HVNR study[J]. CHEMOSPHERE,2014,108:168-174.
APA Wu, Shaowei.,Deng, Furong.,Hao, Yu.,Wang, Xin.,Zheng, Chanjuan.,...&Guo, Xinbiao.(2014).Fine particulate matter, temperature, and lung function in healthy adults: Findings from the HVNR study.CHEMOSPHERE,108,168-174.
MLA Wu, Shaowei,et al."Fine particulate matter, temperature, and lung function in healthy adults: Findings from the HVNR study".CHEMOSPHERE 108(2014):168-174.
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