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学科主题: 公共卫生
题名:
Fine particulate matter, temperature, and lung function in healthy adults: Findings from the HVNR study
作者: Wu, Shaowei1; Deng, Furong1; Hao, Yu1; Wang, Xin1; Zheng, Chanjuan1; Lv, Haibo1; Lu, Xiuling1; Wei, Hongying1; Huang, Jing1; Qin, Yu1; Shima, Masayuki2; Guo, Xinbiao1
关键词: Air pollution ; Lung function ; Particulate matter ; Peak expiratory flow ; Temperature
刊名: CHEMOSPHERE
发表日期: 2014-08-01
DOI: 10.1016/j.chemosphere.2014.01.032
卷: 108, 页:168-174
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Environmental Sciences
研究领域[WOS]: Environmental Sciences & Ecology
关键词[WOS]: HEART-RATE-VARIABILITY ; PEAK EXPIRATORY FLOW ; AIR-POLLUTION ; CHEMICAL-CONSTITUENTS ; EXPOSURE ; PANEL ; ASSOCIATION ; MORTALITY ; DISEASE ; ASTHMA
英文摘要:

Both ambient particulate air pollution and temperature alterations have been associated with adverse human health effects, but the interactive effect of ambient particulate and temperature on human health remains uncertain. The present study investigated the effects of ambient particulate matter with an aerodynamic diameter <= 2.5 mu m (PM2.5) and temperature on human lung function simultaneously in a panel of 21 healthy university students from the Healthy Volunteer Natural Relocation (HVNR) study in the context of suburban/urban air pollution in Beijing, China. Each study subject used an electronic diary meter to record peak expiratory flow (PEF) and forced expiratory volume in 1 s (FEV1) twice a day for 6 months in three periods before and after relocating from a suburban area to an urban area with changing ambient PM2.5 and temperature levels in Beijing. Hourly-averaged environmental data were obtained from central air-monitoring sites. Exposure effects were estimated using generalized linear mixed models controlling for potential confounders. Study subjects provided 6494 daily measurements on PEF and 6460 daily measurements on FEV1 over the study. PM2.5 was associated with reductions in evening PEF and morning/evening FEV1 whereas temperature was associated with reductions in morning PEF. The estimated PM2.5 effects on evening PEF and morning/evening FEV1 in the presence of high temperature were generally stronger than those in the presence of low temperature, and the estimated temperature effects on morning/evening PEF and morning FEV1 in the presence of high PM2.5 were also generally stronger than those in the presence of low PM2.5. For example, there were a 2.47% (95% confidence interval: -4.24, -0.69) reduction and a 0.78% (95% confidence interval: -1.59,0.03) reduction in evening PEF associated with an interquartile range increase (78.7 mu g/m(3)) in PM2.5 at 4-d moving average in the presence of high temperature (>= 21.6 degrees C) and low temperature (<21.6 degrees C), respectively. Our findings suggest that ambient particulate and temperature may interact synergistically to cause adverse respiratory health effects. (C) 2014 Elsevier Ltd. All rights reserved.

语种: 英语
所属项目编号: 81072267 ; 2006BAI19B06 ; 2012AA062804
项目资助者: National Natural Science Foundation of China ; National Key Technologies R&amp ; D Program of China ; National High Technology Research and Development Program of China ; Ministry of Education of the People&prime ; s Republic of China
WOS记录号: WOS:000337881600022
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59785
Appears in Collections:北京大学公共卫生学院_期刊论文

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作者单位: 1.Peking Univ, Sch Publ Hlth, Dept Occupat & Environm Hlth Sci, Beijing 100191, Peoples R China
2.Hyogo Coll Med, Dept Publ Hlth, Nishinomiya, Hyogo, Japan

Recommended Citation:
Wu, Shaowei,Deng, Furong,Hao, Yu,et al. Fine particulate matter, temperature, and lung function in healthy adults: Findings from the HVNR study[J]. CHEMOSPHERE,2014,108:168-174.
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