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学科主题: 药学
题名:
Performance Evaluation of Charged Aerosol and Evaporative Light Scattering Detection for the Determination of Ginsenosides by LC
作者: Wang, Li1,2; He, Wen-Shun1; Yan, Hai-Xia1,2; Jiang, Yong1; Bi, Kai-Shun2; Tu, Peng-Fei1,2
关键词: Column liquid chromatography-charged aerosol detection ; Evaporative light scattering detection ; UV detection ; Ginsenosides
刊名: CHROMATOGRAPHIA
发表日期: 2009-08-01
DOI: 10.1365/s10337-009-1192-y
卷: 70, 期:3-4, 页:603-608
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biochemical Research Methods ; Chemistry, Analytical
研究领域[WOS]: Biochemistry & Molecular Biology ; Chemistry
关键词[WOS]: PRESSURIZED LIQUID EXTRACTION ; PANAX-NOTOGINSENG ; SHENMAI-INJECTION ; DIFFERENT PARTS ; HPLC-ELSD ; CHROMATOGRAPHY ; SAPONINS ; GINSENG ; IDENTIFICATION ; ULTRAVIOLET
英文摘要:

A sensitive LC-CAD method was developed for simultaneous determination of seven major triterpenoid saponins, namely ginsenosides Rg(1), Re, Rb-1, Rc, Rb-2, Rb-3 and Rd in Panax ginseng C. A. Meyer, a commonly used traditional Chinese medicine. This CAD method was evaluated in sensitivity, linearity and reproducibility compared to ELSD and UV. It was found the developed method has improved sensitivity, linearity and reproducibility compared to ELSD. This method was successfully applied to analyze the ginsenosides in ten samples of Panax ginseng. The validation results indicated that the improved method can be utilized as another approach for quality control of P. ginseng.

语种: 英语
所属项目编号: 30525043
项目资助者: Outstanding Youth Science Fund of National Natural Science Foundation of China
WOS记录号: WOS:000268995600036
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59788
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
2.Shenyang Pharmaceut Univ, Sch Pharm, Shenyang 110016, Peoples R China

Recommended Citation:
Wang, Li,He, Wen-Shun,Yan, Hai-Xia,et al. Performance Evaluation of Charged Aerosol and Evaporative Light Scattering Detection for the Determination of Ginsenosides by LC[J]. CHROMATOGRAPHIA,2009,70(3-4):603-608.
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