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Performance Evaluation of Charged Aerosol and Evaporative Light Scattering Detection for the Determination of Ginsenosides by LC
Wang, Li1,2; He, Wen-Shun1; Yan, Hai-Xia1,2; Jiang, Yong1; Bi, Kai-Shun2; Tu, Peng-Fei1,2
关键词Column liquid chromatography-charged aerosol detection Evaporative light scattering detection UV detection Ginsenosides
刊名CHROMATOGRAPHIA
2009-08-01
DOI10.1365/s10337-009-1192-y
70期:3-4页:603-608
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemical Research Methods ; Chemistry, Analytical
资助者Outstanding Youth Science Fund of National Natural Science Foundation of China ; Outstanding Youth Science Fund of National Natural Science Foundation of China
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry
关键词[WOS]PRESSURIZED LIQUID EXTRACTION ; PANAX-NOTOGINSENG ; SHENMAI-INJECTION ; DIFFERENT PARTS ; HPLC-ELSD ; CHROMATOGRAPHY ; SAPONINS ; GINSENG ; IDENTIFICATION ; ULTRAVIOLET
英文摘要

A sensitive LC-CAD method was developed for simultaneous determination of seven major triterpenoid saponins, namely ginsenosides Rg(1), Re, Rb-1, Rc, Rb-2, Rb-3 and Rd in Panax ginseng C. A. Meyer, a commonly used traditional Chinese medicine. This CAD method was evaluated in sensitivity, linearity and reproducibility compared to ELSD and UV. It was found the developed method has improved sensitivity, linearity and reproducibility compared to ELSD. This method was successfully applied to analyze the ginsenosides in ten samples of Panax ginseng. The validation results indicated that the improved method can be utilized as another approach for quality control of P. ginseng.

语种英语
所属项目编号30525043
资助者Outstanding Youth Science Fund of National Natural Science Foundation of China ; Outstanding Youth Science Fund of National Natural Science Foundation of China
WOS记录号WOS:000268995600036
引用统计
被引频次:8[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/59788
专题北京大学药学院
作者单位1.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
2.Shenyang Pharmaceut Univ, Sch Pharm, Shenyang 110016, Peoples R China
推荐引用方式
GB/T 7714
Wang, Li,He, Wen-Shun,Yan, Hai-Xia,et al. Performance Evaluation of Charged Aerosol and Evaporative Light Scattering Detection for the Determination of Ginsenosides by LC[J]. CHROMATOGRAPHIA,2009,70(3-4):603-608.
APA Wang, Li,He, Wen-Shun,Yan, Hai-Xia,Jiang, Yong,Bi, Kai-Shun,&Tu, Peng-Fei.(2009).Performance Evaluation of Charged Aerosol and Evaporative Light Scattering Detection for the Determination of Ginsenosides by LC.CHROMATOGRAPHIA,70(3-4),603-608.
MLA Wang, Li,et al."Performance Evaluation of Charged Aerosol and Evaporative Light Scattering Detection for the Determination of Ginsenosides by LC".CHROMATOGRAPHIA 70.3-4(2009):603-608.
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