IR@PKUHSC  > 北京大学第三临床医学院  > 药剂科
学科主题临床医学
Fast and Reliable Determination of Voriconazole in Human Plasma by LC-APCI-MS/MS
Xiong, Xin1,2; Duan, Jingli1; Zhai, Suodi1; Wang, Lijue1; Lan, Xi3
关键词voriconazole liquid chromatography coupled with atmospheric pressure chemical ionization tandem mass spectrometry (LC-APCI-MS/MS) human plasma
刊名BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
2010-10-01
DOI10.1271/bbb.100474
74期:10页:2151-2153
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Chemistry, Applied ; Food Science & Technology
研究领域[WOS]Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Chemistry ; Food Science & Technology
关键词[WOS]TANDEM MASS-SPECTROMETRY ; PERFORMANCE LIQUID-CHROMATOGRAPHY ; DOSE-ESCALATION ; ESI-MS ; SERUM ; PHARMACOKINETICS ; QUANTIFICATION ; ELECTROSPRAY ; VALIDATION ; SAMPLES
英文摘要

A fast and reliable liquid chromatography coupled With atmospheric pressure chemical ionization tandem mass spectrometry (LC-APCI-MS/MS) method was developed and validated for the quantification of voriconazole in human plasma. The proposed method was validated in a linear range of 50-10,000 ng/ml, and the total run time was 1.5 min. This method was successfully used to support routine therapeutic drug monitoring of voriconazole.

语种英语
WOS记录号WOS:000283624900037
引用统计
被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/59838
专题北京大学第三临床医学院_药剂科
作者单位1.Peking Univ Third Hosp, Dept Pharm, Beijing 100191, Peoples R China
2.Peking Univ, Therapeut Drug Monitoring & Clin Toxicol Ctr, Beijing 100191, Peoples R China
3.Peking Univ, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Xiong, Xin,Duan, Jingli,Zhai, Suodi,et al. Fast and Reliable Determination of Voriconazole in Human Plasma by LC-APCI-MS/MS[J]. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY,2010,74(10):2151-2153.
APA Xiong, Xin,Duan, Jingli,Zhai, Suodi,Wang, Lijue,&Lan, Xi.(2010).Fast and Reliable Determination of Voriconazole in Human Plasma by LC-APCI-MS/MS.BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY,74(10),2151-2153.
MLA Xiong, Xin,et al."Fast and Reliable Determination of Voriconazole in Human Plasma by LC-APCI-MS/MS".BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 74.10(2010):2151-2153.
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