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学科主题: 临床医学
题名:
Levels and congener profiles of polybrominated diphenyl ethers (PBDEs) in primipara breast milk from Shenzhen and exposure risk for breast-fed infants
作者: Zhang, Jian Gang1,2; Sun, Xiao Wei2; Ai, Hua1
刊名: JOURNAL OF ENVIRONMENTAL MONITORING
发表日期: 2012-03-01
DOI: 10.1039/c2em10739b
卷: 14, 期:3, 页:893-900
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Analytical ; Environmental Sciences
研究领域[WOS]: Chemistry ; Environmental Sciences & Ecology
关键词[WOS]: BROMINATED FLAME RETARDANTS ; POLYCHLORINATED-BIPHENYLS PCBS ; MOTHERS MILK ; SOUTH CHINA ; ORGANOCHLORINE PESTICIDES ; CORD SERUM ; WOMEN ; WORKERS ; ACCUMULATION ; POLLUTANTS
英文摘要:

This study aimed at revealing the levels of polybrominated diphenyl ethers (PBDEs) in breast milk from primipara in Shenzhen (China), and estimating daily intake of PBDEs for breast-fed infants. Concentrations of 7 PBDEs were measured in 60 breast milk samples by isotope dilution HRGC/HRMS (high-resolution gas chromatography/high-resolution mass spectrometry). The intake of PBDEs for breast-fed infants was estimated based on the infant′s daily milk consumption. The range of total concentration of 7 PBDEs congeners in samples was 2.6-188.6 ng g(-1) lipid (mean: 14.8 ng g(-1) lipid; median: 7.2 ng g(-1) lipid). The mean estimated daily intake of PBDEs by breast-fed infants ranged from 9.9 to 335.9 ng kg(-1) body weight (bw) per day (mean: 52.5 ng kg(-1) bw per day; median: 28.6 ng kg(-1) bw per day). The levels of PBDEs body burden in the recruited mothers of Shenzhen were higher than those reported previously for the general population from other areas in China. No significant correlations were found between the body burden of PBDEs and the mothers′ age, pre-pregnancy BMI, dietary habits, duration of residence in Shenzhen, weight and length of the newborns. BDE-47 and BDE-153 were major PBDE congeners in milk samples, while the congeners of BDE-183 and BDE-28 were also high in Shenzhen. The situation may be attributed to the special economic pattern including electronic production in Shenzhen in the past three decades. Continuous surveillance on PBDEs levels in human milk is needed in order to accurately evaluate the environmental impact of PBDEs to human health in Shenzhen.

语种: 英语
所属项目编号: lzujbky - 2010 - 125
项目资助者: Fundamental Research Funds for the Central Universities
WOS记录号: WOS:000300875100017
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59845
Appears in Collections:北京大学第三临床医学院_运动医学研究所_期刊论文

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作者单位: 1.Peking Univ, Hosp 3, Inst Sports Med, Nutr & Biochem Lab, Beijing 100191, Peoples R China
2.Lanzhou Univ, Inst Pathol, Lanzhou 730000, Gansu, Peoples R China

Recommended Citation:
Zhang, Jian Gang,Sun, Xiao Wei,Ai, Hua. Levels and congener profiles of polybrominated diphenyl ethers (PBDEs) in primipara breast milk from Shenzhen and exposure risk for breast-fed infants[J]. JOURNAL OF ENVIRONMENTAL MONITORING,2012,14(3):893-900.
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