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学科主题: 临床医学
题名:
Intercellular Transportation of Quantum Dots Mediated by Membrane Nanotubes
作者: He, Kangmin2,3; Luo, Wangxi1; Zhang, Yuliang1; Liu, Fei2,3; Liu, Da1; Xu, Li1; Qin, Lei2,3; Xiong, Chunyang2,3; Lu, Zhizhen2,3; Fang, Xiaohong1; Zhang, Youyi2,3
关键词: quantum dots ; membrane nanotubes ; intercellular transportation ; single particle tracking ; molecular motor
刊名: ACS NANO
发表日期: 2010-06-01
DOI: 10.1021/nn1002198
卷: 4, 期:6, 页:3015-3022
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary
研究领域[WOS]: Chemistry ; Science & Technology - Other Topics ; Materials Science
关键词[WOS]: TUG-OF-WAR ; LIVING CELLS ; TUNNELING NANOTUBES ; IN-VIVO ; MICROTUBULE MOTORS ; CYTOPLASMIC DYNEIN ; ANIMAL-CELLS ; TRACKING ; DELIVERY ; KINESIN
英文摘要:

In this work, we reported that the quantum dot (QD) nanoparticles could be actively transported in the membrane nanotubes between cardiac myocytes. Single particle imaging and tracking of QDs revealed that most QDs moved in a bidirectional mode along the membrane nanotubes with a mean velocity of 1.23 mu m/s. The results suggested that QDs moving in the nanotubes were coordinately motivated by molecular motors. It provides new information for the study of intercellular transportation of nanoparticles.

语种: 英语
所属项目编号: 2007CB935601 ; 90713024 ; 30821001 ; 20821003 ; 307001
项目资助者: National Basic Research Program of China ; National Natural Science Foundation of China ; Chinese Academy of Sciences ; Chinese Ministry of Education
WOS记录号: WOS:000278888600008
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/59931
Appears in Collections:北京大学第三临床医学院_期刊论文

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作者单位: 1.Chinese Acad Sci, Inst Chem, Key Lab Mol Nanostruct & Nanotechnol, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China
2.Peking Univ, Minist Educ Key Lab Mol Cardiovasc Sci, Hosp 3, Acad Adv Interdisciplinary Studies, Beijing 100191, Peoples R China
3.Peking Univ, Minist Educ Key Lab Mol Cardiovasc Sci, Hosp 3, Inst Vasc Med, Beijing 100191, Peoples R China

Recommended Citation:
He, Kangmin,Luo, Wangxi,Zhang, Yuliang,et al. Intercellular Transportation of Quantum Dots Mediated by Membrane Nanotubes[J]. ACS NANO,2010,4(6):3015-3022.
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