IR@PKUHSC  > 北京大学药学院  > 天然药物学系
学科主题药学
Three new isoflavone glycosides from Tongmai granules
Wang, Fu-Rong1; Yang, Xiu-Wei1; Zhang, Ying2; Liu, Jian-Xun2; Yang, Xin-Bao2,3; Liu, Yang3; Shi, Ren-Bing3
关键词Tongmai granules 3&prime -methoxydaidzein-7 4&prime -di-O--d-glucopyranoside biochanin A-8-C--d-apiofuranosyl-(16)-O--d-glucopyranoside daidzein-7-O--d-glucopyranosyl-(14)-O--d-glucopyranoside DPPH radical-scavenging activity
刊名JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
2011
DOI10.1080/10286020.2011.556090
13期:4页:319-329
收录类别SCI ; IC
文章类型Article
WOS标题词Science & Technology
类目[WOS]Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
资助者&prime ; Major New Medicine Project&prime ; in Megaprojects of Science Research of China ; &prime ; Major New Medicine Project&prime ; in Megaprojects of Science Research of China
研究领域[WOS]Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]PUERARIA-LOBATA ; OFFICINALIS
英文摘要

Three new isoflavone glycosides, 3′-methoxydaidzein-7,4′-di-O--d-glucopyranoside (1), biochanin A-8-C--d-apiofuranosyl-(16)-O--d-glucopyranoside (2), daidzein-7-O--d-glucopyranosyl-(14)-O--d-glucopyranoside (3), and a new natural isoflavone glycoside, daidzein-7-O--d-glucopyranosyl-(14)-O--d-glucopyranoside (4) were isolated along with 18 known isoflavones from the EtOAc and n-BuOH fractions of the aqueous extraction of Tongmai granules. All the isoflavones were obtained and determined for the first time from Tongmai granules. The structures of these compounds were elucidated by spectral methods. It was confirmed that the compounds 1-4 were originally from Puerariae Lobatae Radix based on HPLC-DAD analysis of the crude drug extract. The isoflavones isolated were tested for their antioxidative activities by measuring the capacities of scavenging the 2,2′-diphenyl-1-picrylhydrazyl radical.

语种英语
所属项目编号2009ZX09502-006
资助者&prime ; Major New Medicine Project&prime ; in Megaprojects of Science Research of China ; &prime ; Major New Medicine Project&prime ; in Megaprojects of Science Research of China
WOS记录号WOS:000289249300006
Citation statistics
Cited Times:5[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60001
Collection北京大学药学院_天然药物学系
作者单位1.Peking Univ, Sch Pharmaceut Sci, Dept Nat Med, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
2.China Acad Chinese Med Sci, Xiyuan Hosp, Res Ctr, Beijing 100091, Peoples R China
3.Beijing Univ Chinese Med, Beijing 100029, Peoples R China
Recommended Citation
GB/T 7714
Wang, Fu-Rong,Yang, Xiu-Wei,Zhang, Ying,et al. Three new isoflavone glycosides from Tongmai granules[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2011,13(4):319-329.
APA Wang, Fu-Rong.,Yang, Xiu-Wei.,Zhang, Ying.,Liu, Jian-Xun.,Yang, Xin-Bao.,...&Shi, Ren-Bing.(2011).Three new isoflavone glycosides from Tongmai granules.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,13(4),319-329.
MLA Wang, Fu-Rong,et al."Three new isoflavone glycosides from Tongmai granules".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 13.4(2011):319-329.
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