IR@PKUHSC  > 北京大学药学院
学科主题药学
Iterative one-pot syntheses of chitotetroses
Huang, Lijun; Wang, Zhen; Li, Xiaoning; Ye, Xin-shan; Huang, Xuefei
关键词iterative one-pot synthesis chitotetrose reactivity independent
刊名CARBOHYDRATE RESEARCH
2006-07-24
DOI10.1016/j.carres.2006.01.007
341期:10页:1669-1679
收录类别SCI ; IC ; CCR
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Chemistry, Applied ; Chemistry, Organic
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry
关键词[WOS]ACCEPTOR SELECTIVITY RDAS ; OLIGOSACCHARIDE SYNTHESIS ; GLYCOSYL ACCEPTORS ; RHIZOBIUM-MELILOTI ; CHEMICAL-SYNTHESIS ; REACTIVITY ; DERIVATIVES ; DONOR ; STRATEGY ; THIOGLYCOSIDES
英文摘要

Rapid syntheses of chitotetrose derivatives were achieved in good yields using the newly developed reactivity independent iterative one-pot strategy. The protective groups on donors and acceptors were independently evaluated allowing matching of the two partners in glycosylation. No anomeric reactivity adjustments or intermediate purification were necessary thus significantly improving the overall synthetic efficiency. Only near stoichiometric amounts of building blocks were required for the assembly of target molecules further highlighting the potential of the iterative one-pot method in complex oligosaccharide synthesis. (c) 2006 Elsevier Ltd. All rights reserved.

语种英语
WOS记录号WOS:000238563300038
Citation statistics
Cited Times:38[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60043
Collection北京大学药学院
作者单位1.Univ Toledo, Dept Chem, Toledo, OH 43606 USA
2.Peking Univ, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100083, Peoples R China
Recommended Citation
GB/T 7714
Huang, Lijun,Wang, Zhen,Li, Xiaoning,et al. Iterative one-pot syntheses of chitotetroses[J]. CARBOHYDRATE RESEARCH,2006,341(10):1669-1679.
APA Huang, Lijun,Wang, Zhen,Li, Xiaoning,Ye, Xin-shan,&Huang, Xuefei.(2006).Iterative one-pot syntheses of chitotetroses.CARBOHYDRATE RESEARCH,341(10),1669-1679.
MLA Huang, Lijun,et al."Iterative one-pot syntheses of chitotetroses".CARBOHYDRATE RESEARCH 341.10(2006):1669-1679.
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