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学科主题: 药学
题名:
1,10-Phenanthroline platinum(II) complex: a simple molecule for efficient G-quadruplex stabilization
作者: Wang, Jin-Tao1; Zheng, Xiao-Hui1; Xia, Qing2; Mao, Zong-Wan1,2; Ji, Liang-Nian1; Wang, Kui2
刊名: DALTON TRANSACTIONS
发表日期: 2010
DOI: 10.1039/c0dt00211a
卷: 39, 期:31, 页:7214-7216
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Inorganic & Nuclear
研究领域[WOS]: Chemistry
关键词[WOS]: TELOMERASE ACTIVITY ; QUARTET STRUCTURES ; DNA ; LIGANDS ; INHIBITION ; TARGETS ; DERIVATIVES ; PROMOTER ; SEQUENCE ; AFFINITY
英文摘要:

Two simple complexes [Pt(phen)(2)](PF(6))(2) and [Pt(bpy)(2)](PF(6))(2) exhibit high stabilization potential for G-quadruplex DNA with [Pt(phen)(2)](PF(6))(2) possessing higher capability due to its greater planarity.

语种: 英语
所属项目编号: 20821001 ; 20831006 ; 20725103 ; 30770494 ; 9351027501000003 ; 2007CB815306
项目资助者: Fundamental Research Funds for the Central Universities ; National Natural Science Foundation of China ; Guangdong Provincial Natural Science Foundation ; 973 Program
WOS记录号: WOS:000280527300004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60044
Appears in Collections:北京大学药学院_化学生物学系_期刊论文

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作者单位: 1.Sun Yat Sen Univ, MOE Key Lab Bioinorgan & Synthet Chem, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China
2.Peking Univ, State Key Lab Nat & Biomimet Drug, Dept Biol Chem, Sch Pharmaceut Sci, Beijing 100191, Peoples R China

Recommended Citation:
Wang, Jin-Tao,Zheng, Xiao-Hui,Xia, Qing,et al. 1,10-Phenanthroline platinum(II) complex: a simple molecule for efficient G-quadruplex stabilization[J]. DALTON TRANSACTIONS,2010,39(31):7214-7216.
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