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学科主题: 药学
题名:
Synthesis of conformationally locked isonucleosides: 2 ′-deoxy-2 ′-nucleobase-5 ′-deoxy-1 ′,4 ′ : 3 ′,6 ′-dianhydro-D-mannitol
作者: Tian, XB; Zhang, L; Min, JM; Zhang, LH; Lu, Y; Jiang, RW; Zheng, QT
关键词: bicyclic isonucleoside ; locked conformation ; synthesis
刊名: CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
发表日期: 2001-05-01
卷: 17, 期:2, 页:178-186
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
英文摘要:

Novel bicyclic isonucleosides, 2′ -deoxl-2′ -nucleobase-5′ -deoxy-1′ ,4′ : 3′ ,6′-dianhydro-D-mannitol 10a-10c, were synthesized from D-glucose. The computer-assisted molecular simulation indicated that the sugar conformations of compounds 10a-10c were restricted to N-conformation.

语种: 英语
WOS记录号: WOS:000169236400009
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60050
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Beijing Med Univ, Sch Pharmaceut Sci, Beijing 100083, Peoples R China
2.Peking Union Med Coll, Inst Mat Med, Beijing 100050, Peoples R China
3.Chinese Acad Med Sci, Beijing 100050, Peoples R China

Recommended Citation:
Tian, XB,Zhang, L,Min, JM,et al. Synthesis of conformationally locked isonucleosides: 2 ′-deoxy-2 ′-nucleobase-5 ′-deoxy-1 ′,4 ′ : 3 ′,6 ′-dianhydro-D-mannitol[J]. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,2001,17(2):178-186.
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