北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学药学院  > 期刊论文
学科主题: 药学
题名:
Synthesis of 3-N-Sugar-substituted-2, 4(1H,3H)-quinazolinediones as Anti-Angiogenesis Agents
作者: Huang, Conghai; Meng, Xiangbao; Cui, Jingrong; Li, Zhongjun
关键词: quinazolinediones ; anti-angiogenesis ; triphosgene
刊名: MOLECULES
发表日期: 2009-07-01
DOI: 10.3390/molecules14072447
卷: 14, 期:7, 页:2447-2457
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Organic
研究领域[WOS]: Chemistry
关键词[WOS]: AMINOPEPTIDASE INHIBITORS ; 2,4-QUINAZOLINEDIONES ; DERIVATIVES ; GLUCOSAMINE
英文摘要:

A series of novel 3-N-sugar-substituted quinazolinediones were synthesized through the cyclization of the intermediate 2-aminobenzamides using triphosgene as the condensing reagent. Their anti-angiogenesis activities were investigated. The compound 3( 2′-aminoglucosyl)-2,4-(1H,3H)-quinazolinedione, (5d) showed good anti-angiogenesis activity.

语种: 英语
所属项目编号: 30672525 ; 20732001
项目资助者: National Science Foundation of China
WOS记录号: WOS:000268318300011
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60100
Appears in Collections:北京大学药学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

Recommended Citation:
Huang, Conghai,Meng, Xiangbao,Cui, Jingrong,et al. Synthesis of 3-N-Sugar-substituted-2, 4(1H,3H)-quinazolinediones as Anti-Angiogenesis Agents[J]. MOLECULES,2009,14(7):2447-2457.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Huang, Conghai]'s Articles
[Meng, Xiangbao]'s Articles
[Cui, Jingrong]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Huang, Conghai]‘s Articles
[Meng, Xiangbao]‘s Articles
[Cui, Jingrong]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace