|Observed Prevalence of Congenital Heart Defects From a Surveillance Study in China|
|Zhang, Yali1; Riehle-Colarusso, Tiffany3; Correa, Adolfo3; Li, Song2,4; Feng, Xinheng4; Gindler, Jacqueline3; Lin, Hui2; Webb, Catherine5; Li, Wei2; Trines, Jean6; Berry, Robert J.3; Yeung, Lorraine3; Luo, Ying7; Jiang, Meifang8; Chen, Hua; Sun, Xiamei10; Li, Zhu1|
|关键词||congenital heart defects fetal echocardiography neonatal echocardiography prevalence|
|刊名||JOURNAL OF ULTRASOUND IN MEDICINE|
|WOS标题词||Science & Technology|
|类目[WOS]||Acoustics ; Radiology, Nuclear Medicine & Medical Imaging|
|研究领域[WOS]||Acoustics ; Radiology, Nuclear Medicine & Medical Imaging|
|关键词[WOS]||PRENATAL-DIAGNOSIS ; BIRTH PREVALENCE ; DISEASE ; POPULATION ; EXPERIENCE ; CHILDREN ; ENGLAND|
Objectives-The purpose of this study was to estimate the prevalence of major and minor congenital heart defects among fetuses and neonates using sonography in a general population of 4 areas surrounding Shanghai, China.
Methods-Pregnant women were recruited between April 2004 and December 2005 in Jiaxing City, Suzhou City, Changshu County, and Haining County. All participants could have 3 sonographic examinations performed by specially trained physicians regardless of medical indication: a fetal sonographic screen and fetal echocardiography between 20 and 28 weeks′ gestation and neonatal echocardiography. Diagnoses of congenital heart defects were made on the basis of review of all available scans by an international group of experts in pediatric cardiology. Prevalence rates were calculated per 1000 births.
Results-Among 4006 scanned fetuses and neonates, there were 75 congenital heart defects, including 12 major defects. The observed prevalence for all congenital heart defects was 18.7 (95% confidence interval, 14.8-23.5) per 1000 births, and the prevalence for major defects was 3.0 (95% confidence interval, 1.6-5.2) per 1000 births. The most common defects were ventricular septal defects (n = 47 [62.7%]);atrial septal defects (n = 14 [18.7%]), tetralogy of Fallot (n = 4 [5.3%]), and hypoplastic left heart syndrome (n = 3 [4.0%]).
Conclusions-The prevalence of all congenital heart defects in the 4 areas of China studied was higher than that reported in other countries, with ventricular septal defects being the most frequent defects. Our data likely reflect a better estimate of the total prevalence of congenital heart defects in China than reported previously.
|资助机构||Centers for Disease Control and Prevention|
|作者单位||1.Suzhou Mother & Child Hlth Care Ctr, Suzhou, Peoples R China|
2.Jiaxing Maternal & Child Hlth Care Hosp, Jiaxing, Peoples R China
3.Haining Maternal & Child Hlth Care Hosp, Haining, Peoples R China
4.Peking Univ, Hosp 3, Beijing 100191, Peoples R China
5.Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA
6.Changshu Maternal & Child Hlth Care Hosp, Changshu, Peoples R China
7.Peking Univ, Hlth Sci Ctr, Sch Publ Hlth, Beijing 100191, Peoples R China
8.Peking Univ, Natl Ctr Maternal & Infant Hlth, Sch Publ Hlth, Beijing 100191, Peoples R China
9.Ctr Dis Control & Prevent, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA USA
10.Hosp Sick Children, Toronto, ON M5G 1X8, Canada
|Zhang, Yali,Riehle-Colarusso, Tiffany,Correa, Adolfo,et al. Observed Prevalence of Congenital Heart Defects From a Surveillance Study in China[J]. JOURNAL OF ULTRASOUND IN MEDICINE,2011,30(7):989-995.|
|APA||Zhang, Yali.,Riehle-Colarusso, Tiffany.,Correa, Adolfo.,Li, Song.,Feng, Xinheng.,...&Li, Zhu.(2011).Observed Prevalence of Congenital Heart Defects From a Surveillance Study in China.JOURNAL OF ULTRASOUND IN MEDICINE,30(7),989-995.|
|MLA||Zhang, Yali,et al."Observed Prevalence of Congenital Heart Defects From a Surveillance Study in China".JOURNAL OF ULTRASOUND IN MEDICINE 30.7(2011):989-995.|