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学科主题: 公共卫生
题名:
Effects of high-protein diets on body weight, glycaemic control, blood lipids and blood pressure in type 2 diabetes: meta-analysis of randomised controlled trials
作者: Dong, Jia-Yi1; Zhang, Zeng-Li2; Wang, Pei-Yu3; Qin, Li-Qiang1
关键词: High-protein diets ; Metabolic risk factors ; Type 2 diabetes ; Randomised controlled trials ; Meta-analyses
刊名: BRITISH JOURNAL OF NUTRITION
发表日期: 2013-09-14
DOI: 10.1017/S0007114513002055
卷: 110, 期:5, 页:781-789
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Nutrition & Dietetics
研究领域[WOS]: Nutrition & Dietetics
关键词[WOS]: LOW-CARBOHYDRATE-DIET ; LOW-FAT DIET ; GLUCOSE CONTROL ; MELLITUS ; RISK ; PREVALENCE ; OVERWEIGHT ; EXERCISE ; IMPROVES ; DISEASE
英文摘要:

High-protein diets are popular for weight management, but the health effects of such diets in diabetic persons are inconclusive. The aim of the present meta-analysis was to examine the effects of high-protein diets on body weight and metabolic risk factors in patients with type 2 diabetes. We searched the PubMed and Cochrane Library databases for relevant randomised trials up to August 2012. Either a fixed-or a random-effects model was used to combine the net changes in each outcome from baseline to the end of the intervention. Overall, nine trials including a total of 418 diabetic patients met our inclusion criteria. The study duration ranged from 4 to 24 weeks. The actual intake of dietary protein ranged from 25 to 32% of total energy in the intervention groups and from 15 to 20% in the control groups. Compared with the control diets, high-protein diets resulted in more weight loss (pooled mean difference: -2.08, 95% CI -3.25, -0.90 kg). High-protein diets significantly decreased glycated Hb A(1C) (HbA(1C)) levels by 0.52 (95% CI -0.90, -0.14) %, but did not affect the fasting blood glucose levels. There were no differences in lipid profiles. The pooled net changes in systolic and diastolic blood pressure were -3.13 (95% CI -6.58, 0.32) mmHg and -1.86 (95% CI -4.26, 0.56) mmHg, respectively. However, two studies reported a large influence on weight loss and HbA(1C) levels, respectively. In summary, high-protein diets (within 6 months) may have some beneficial effects on weight loss, HbA(1C) levels and blood pressure in patients with type 2 diabetes. However, further investigations are still required to draw a conclusion.

语种: 英语
所属项目编号: 81273067 ; 30771808
项目资助者: National Natural Science Foundation of China
WOS记录号: WOS:000323281500001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60142
Appears in Collections:北京大学公共卫生学院_期刊论文

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作者单位: 1.Soochow Univ, Coll Med, Sch Publ Hlth, Dept Food Hyg & Nutr, Suzhou 215123, Peoples R China
2.Soochow Univ, Coll Med, Sch Publ Hlth, Dept Labor Hyg & Environm Hlth, Suzhou 215123, Peoples R China
3.Peking Univ, Sch Publ Hlth, Dept Social Med & Hlth Educ, Beijing 100871, Peoples R China

Recommended Citation:
Dong, Jia-Yi,Zhang, Zeng-Li,Wang, Pei-Yu,et al. Effects of high-protein diets on body weight, glycaemic control, blood lipids and blood pressure in type 2 diabetes: meta-analysis of randomised controlled trials[J]. BRITISH JOURNAL OF NUTRITION,2013,110(5):781-789.
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