北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第一临床医学院  > 泌尿外科  > 期刊论文
学科主题: 临床医学
题名:
Prognostic Factors in Chinese Patients With Penile Invasive Squamous Cell Carcinoma
作者: Chen, Xiaopeng1; Li, Xuesong1; Garcia, Maurice M.2; Gong, Kan1; Song, Yi1; He, Zhisong1; Zhou, Liqun1
关键词: Penile cancer ; chronological age ; lymph node metastasis ; histological grade
刊名: JOURNAL OF ANDROLOGY
发表日期: 2012-11-01
DOI: 10.2164/jandrol.112.016378
卷: 33, 期:6, 页:1276-1281
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Andrology
研究领域[WOS]: Endocrinology & Metabolism
关键词[WOS]: LYMPH-NODE INVOLVEMENT ; CANCER ; METASTASIS ; DISSECTION ; SURVIVAL ; BIOPSY
英文摘要:

The incidence of penile cancer varies by ethnicity and is not well described among Chinese patients. We performed a retrospective study to assess the prognostic factors in Chinese patients with penile invasive squamous cell carcinoma (SCC). We reviewed the medical records of 83 consecutive patients treated at the National Urological Cancer Center (Beijing, China). The Kaplan-Meier method, log-rank test, and multivariate Cox proportional hazard model were used to identify the prognostic factors predicting for cancer-specific survival (CSS). Univariate and multivariate logistic regression analysis were used to analyze the predictive factors for lymph node metastasis (LNM). A total of 55 patients were followed. Twelve patients (20%) died from the disease during follow-up. By univariate analysis, older age (>= 49 years; P = .048), radical resection (compared with local/partial resection; P = .040), high histological grade (P = .037), and LNM (P < .001) were each associated with poor prognosis. By multivariate analysis, chronological age (P = .011) and LNM (P = .002) were independent prognostic factors. High histological grade (P = .003) was an independent predictive factor for LNM. In our series, chronological age and LNM were independent prognostic factors for CSS. The histological grade, not the tumor stage, was still an influential predictive factor of LNM in Chinese patients with penile SCC.

语种: 英语
WOS记录号: WOS:000312113200029
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60145
Appears in Collections:北京大学第一临床医学院_泌尿外科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Peking Univ, Dept Urol, Hosp 1, Inst Urol,Natl Urol Canc Ctr, Beijing 100034, Peoples R China
2.Univ Calif San Francisco, Dept Urol, San Francisco, CA USA

Recommended Citation:
Chen, Xiaopeng,Li, Xuesong,Garcia, Maurice M.,et al. Prognostic Factors in Chinese Patients With Penile Invasive Squamous Cell Carcinoma[J]. JOURNAL OF ANDROLOGY,2012,33(6):1276-1281.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Chen, Xiaopeng]'s Articles
[Li, Xuesong]'s Articles
[Garcia, Maurice M.]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Chen, Xiaopeng]‘s Articles
[Li, Xuesong]‘s Articles
[Garcia, Maurice M.]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace