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Effect of Modified Roux-en-Y Gastric Bypass Surgery on GLP-1, GIP in Patients with Type 2 Diabetes Mellitus
Xiong, Shao-Wei1; Cao, Jing1; Liu, Xian-Ming1; Deng, Xing-Ming1; Liu, Zeng1; Zhang, Fang-Ting2
刊名GASTROENTEROLOGY RESEARCH AND PRACTICE
2015
DOI10.1155/2015/625196
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Gastroenterology & Hepatology
研究领域[WOS]Gastroenterology & Hepatology
关键词[WOS]BARIATRIC SURGERY ; SLEEVE GASTRECTOMY ; MEDICAL THERAPY ; OBESE-PATIENTS ; METAANALYSIS
英文摘要

The type 2 diabetes mellitus (T2DM) is one of the most serious diseases that threaten public health. Modified gastric bypass surgery has been applied to the treatment of T2DM patients in the 1990s, but the therapeutic mechanism to this function is still unclear. The aim of this study was to further clarify the effect and the mechanism of modified gastric bypass surgery on glucose metabolism in patients with T2DM. In the study, the incretin indexes and blood glucose indexes were analyzed before surgery and 1 week and 1, 3, and 6 months after surgery. The results suggested that modified Roux-en-Y gastric bypass can promote GLP-1 secretion in patients with T2DM, while reducing the secretion of GIP. Thus it could effectively control blood glucose of patients with T2DM.

语种英语
WOS记录号WOS:000357216500001
项目编号JCYJ20130402113802233 ; JC201005260209A
资助机构Basic Research Projects of Shenzhen R&amp ; D Funding in Science and Technology
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60222
专题北京大学深圳医院
作者单位1.Peking Univ, Shenzhen Hosp, Dept Gen Surg, Shenzhen 518036, Guangdong, Peoples R China
2.Peking Univ, Shenzhen Hosp, Cent Lab, Shenzhen 518036, Guangdong, Peoples R China
推荐引用方式
GB/T 7714
Xiong, Shao-Wei,Cao, Jing,Liu, Xian-Ming,et al. Effect of Modified Roux-en-Y Gastric Bypass Surgery on GLP-1, GIP in Patients with Type 2 Diabetes Mellitus[J]. GASTROENTEROLOGY RESEARCH AND PRACTICE,2015.
APA Xiong, Shao-Wei,Cao, Jing,Liu, Xian-Ming,Deng, Xing-Ming,Liu, Zeng,&Zhang, Fang-Ting.(2015).Effect of Modified Roux-en-Y Gastric Bypass Surgery on GLP-1, GIP in Patients with Type 2 Diabetes Mellitus.GASTROENTEROLOGY RESEARCH AND PRACTICE.
MLA Xiong, Shao-Wei,et al."Effect of Modified Roux-en-Y Gastric Bypass Surgery on GLP-1, GIP in Patients with Type 2 Diabetes Mellitus".GASTROENTEROLOGY RESEARCH AND PRACTICE (2015).
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