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学科主题: 临床医学
题名:
Effect of Modified Roux-en-Y Gastric Bypass Surgery on GLP-1, GIP in Patients with Type 2 Diabetes Mellitus
作者: Xiong, Shao-Wei1; Cao, Jing1; Liu, Xian-Ming1; Deng, Xing-Ming1; Liu, Zeng1; Zhang, Fang-Ting2
刊名: GASTROENTEROLOGY RESEARCH AND PRACTICE
发表日期: 2015
DOI: 10.1155/2015/625196
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Gastroenterology & Hepatology
研究领域[WOS]: Gastroenterology & Hepatology
关键词[WOS]: BARIATRIC SURGERY ; SLEEVE GASTRECTOMY ; MEDICAL THERAPY ; OBESE-PATIENTS ; METAANALYSIS
英文摘要:

The type 2 diabetes mellitus (T2DM) is one of the most serious diseases that threaten public health. Modified gastric bypass surgery has been applied to the treatment of T2DM patients in the 1990s, but the therapeutic mechanism to this function is still unclear. The aim of this study was to further clarify the effect and the mechanism of modified gastric bypass surgery on glucose metabolism in patients with T2DM. In the study, the incretin indexes and blood glucose indexes were analyzed before surgery and 1 week and 1, 3, and 6 months after surgery. The results suggested that modified Roux-en-Y gastric bypass can promote GLP-1 secretion in patients with T2DM, while reducing the secretion of GIP. Thus it could effectively control blood glucose of patients with T2DM.

语种: 英语
所属项目编号: JCYJ20130402113802233 ; JC201005260209A
项目资助者: Basic Research Projects of Shenzhen R&amp ; D Funding in Science and Technology
WOS记录号: WOS:000357216500001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60222
Appears in Collections:北京大学深圳医院_期刊论文

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作者单位: 1.Peking Univ, Shenzhen Hosp, Dept Gen Surg, Shenzhen 518036, Guangdong, Peoples R China
2.Peking Univ, Shenzhen Hosp, Cent Lab, Shenzhen 518036, Guangdong, Peoples R China

Recommended Citation:
Xiong, Shao-Wei,Cao, Jing,Liu, Xian-Ming,et al. Effect of Modified Roux-en-Y Gastric Bypass Surgery on GLP-1, GIP in Patients with Type 2 Diabetes Mellitus[J]. GASTROENTEROLOGY RESEARCH AND PRACTICE,2015.
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