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学科主题: 临床医学
题名:
Cauda equina syndrome caused by isolated spinal extramedullary-intradural cauda equina metastasis is the primary symptom of small cell lung cancer: a case report and review of the literatrure
作者: Xiong, Jian; Zhang, Peixun
关键词: Cauda equina syndrome ; small cell lung cancer ; extramedullary intradural spinal metastasis
刊名: INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
发表日期: 2015
卷: 8, 期:6, 页:10044-10050
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, Research & Experimental
研究领域[WOS]: Research & Experimental Medicine
关键词[WOS]: CARCINOID-TUMOR ; INFILTRATION ; DIAGNOSIS ; NEOPLASMS
英文摘要:

Objectives: To describe a case of extramedullary-intradural metastases causing cauda equina syndrome (CES) as the primary syndrome of lung cancer, and to review the pertinent medical literature. Summary of Background Data: Intradural spinal metastasis is rare, accounting for 6% of all spinal metastases. Of all primary lesion types, lung carcinoma is about 40-85%. Extramedullary-intradural metastases of lung cancer causing CES is unusual. Methods: A 55-year-old patient with symptoms of low back pain that radiated to bilateral lower legs with painful paresthesias and piecemeal sphincter disturbances and lead to urinary incontinence, and constipation at last for three months. The MRI showed that there was an isolated, well-demarcated, intradural extramedullary mass at the L3, 4 levels. Results: The patient was admitted to the hospital as the severe cauda equina syndrome (CES) and considering the possibility of nerve system neoplasms for surgery. After a series of examinations, the X-ray and computed tomography (CT) detected a tumor in the left upper lobe with hilar and mediastinal lymph node metastases. The concluded diagnosis through histopathologic examination with immunohistochemistry after the patient received an L3-L4 laminectomy and tumor excision and biopsy was extramedullary-intradural spinal metastasis of the small cell lung cancer (SCLC). The patient had a rapid improvement of the CES. Conclusion: Although the majority of cauda equina tumors are primary tumors, extramedullary-intradural metastasis should be considered before surgery in patients with rapid developed CES.

语种: 英语
所属项目编号: 31271284 ; 31171150 ; 81171146 ; 30971526 ; 31100860 ; 31040043 ; 31371210 81372044 ; BMU20110270 ; 2014013542200 ; SS2015AA020501
项目资助者: Chinese National Natural Science Fund ; Chinese Educational Ministry New Century Excellent Talents Support Project ; Chinese National Ministry of Science and Technology 973 Project ; 863 Project
WOS记录号: WOS:000359295600220
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60286
Appears in Collections:北京大学第二临床医学院_期刊论文

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作者单位: Peking Univ, Peoples Hosp, Dept Trauma & Orthopaed, Beijing 100871, Peoples R China

Recommended Citation:
Xiong, Jian,Zhang, Peixun. Cauda equina syndrome caused by isolated spinal extramedullary-intradural cauda equina metastasis is the primary symptom of small cell lung cancer: a case report and review of the literatrure[J]. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE,2015,8(6):10044-10050.
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