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IR@PKUHSC  > 北京大学第二临床医学院  > 内分泌科  > 期刊论文
学科主题: 临床医学
题名:
Hypoglycaemia, Abnormal Lipids, and Cardiovascular Disease among Chinese with Type 2 Diabetes
作者: Li, Yijun1; Mu, Yiming1; Ji, Qiuhe2; Huang, Qin3; Kuang, Hongyu4; Ji, Linong5; Yang, Xilin6
刊名: BIOMED RESEARCH INTERNATIONAL
发表日期: 2015
DOI: 10.1155/2015/862896
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biotechnology & Applied Microbiology ; Medicine, Research & Experimental
研究领域[WOS]: Biotechnology & Applied Microbiology ; Research & Experimental Medicine
关键词[WOS]: CHRONIC KIDNEY-DISEASE ; BLOOD-GLUCOSE CONTROL ; RISK-FACTORS ; FOLLOW-UP ; REGISTRY ; COMPLICATIONS ; DYSLIPIDEMIA ; ALBUMINURIA ; ASSOCIATION ; PREVALENCE
英文摘要:

We recruited a group of 6713 consecutive Chinese patients with T2D but normal renal and liver function who were admitted to one of 81 top tertiary care hospitals in China. Mild hypoglycaemia was defined as having symptomatic hypoglycaemia in one month before hospitalization. Severe hypoglycaemia was defined as having hypoglycaemia that needed assistance from other people in three months before hospitalization. Prior cardiovascular disease (CVD) was defined as having coronary heart disease, stroke, or peripheral arterial disease. Of 6713 patients, 80 and 304 had severe and mild hypoglycaemia episodes, respectively, and 561 had CVD. Patients with severe and mild hypoglycaemia episodes were more likely to have prior CVD (32.5% versus 16.5% versus 7.7%, P < 0.0001). Both mild and severe hypoglycaemia were associated with increased risk of CVD (adjusted odds ratios (ORs): 2.64, 95% CI: 1.85-3.76 for mild hypoglycaemia; 6.59, 95% CI: 3.79-11.45 for sever hypoglycaemia) than those patients free of hypoglycaemia. Further adjustment for lipid profile did not change these two ORs. In the same way, the ORs of lipid profile for CVD were similar before and after adjustment for hypoglycaemia. We concluded that hypoglycaemia and lipid profile were independently associated with increased risk of CVD.

语种: 英语
项目资助者: Novo Nordisk China
WOS记录号: WOS:000363171500001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60294
Appears in Collections:北京大学第二临床医学院_内分泌科_期刊论文

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作者单位: 1.Chinese Peoples Liberat Army Gen Hosp, Dept Endocrinol, Beijing 100853, Peoples R China
2.4th Mil Med Univ, Xijing Hosp, Dept Endocrinol, Xian 710032, Shaanxi, Peoples R China
3.Changhai Hosp Shanghai, Dept Endocrinol, Shanghai 200433, Peoples R China
4.Harbin Med Univ, Dept Endocrinol, Affiliated Hosp, Harbin 150001, Heilongjiang, Peoples R China
5.Peking Univ, Dept Endocrinol, Peoples Hosp, Beijing 100096, Peoples R China
6.Tianjin Med Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Tianjin 300070, Peoples R China

Recommended Citation:
Li, Yijun,Mu, Yiming,Ji, Qiuhe,et al. Hypoglycaemia, Abnormal Lipids, and Cardiovascular Disease among Chinese with Type 2 Diabetes[J]. BIOMED RESEARCH INTERNATIONAL,2015.
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