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学科主题临床医学
Surgical treatment of primary palmar hyperhidrosis: a prospective randomized study comparing T3 and T4 sympathicotomy
Liu, Yanguo1; Yang, Jie; Liu, Jun1; Yang, Fan1; Jiang, Guanchao1; Li, Jianfeng1; Huang, Yuqing2; Wang, Jun1
关键词Palmar hyperhidrosis Sympathicotomy Sympathectomy Surgery Thoracoscopy
刊名EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
2009-03-01
DOI10.1016/j.ejcts.2008.10.048
35期:3页:398-402
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Cardiac & Cardiovascular Systems ; Respiratory System ; Surgery
研究领域[WOS]Cardiovascular System & Cardiology ; Respiratory System ; Surgery
关键词[WOS]THORACOSCOPIC SYMPATHECTOMY ; TRANSTHORACIC SYMPATHECTOMY ; RIGHT OPERATION ; UPPER-LIMB ; BLOCK ; DENERVATION ; GANGLION ; LOOKING
英文摘要

Objective: Endoscopic thoracic sympathetic surgery was effective for palmar hyperhidrosis (PH), but side effects such as compensatory sweating and over dry hands were common. A multiple centers prospective randomized study was designed to compare the efficiency and side effects of T3 and T4 sympathicotomy in the treatment of PH. Methods: From September 2004 to February 2006, 141 consecutive patients with PH were randomized into two therapeutic groups: group T3 underwent T3 sympathicotomy (n = 68) and group T4 underwent T4 sympathicotomy (n = 73). Improvement of hand sweating, side effects like compensatory sweating or over dry hands, and satisfactory rate of the patients were recorded. Results: There were 78 mates and 63 females. The median age was 26.9 years. The two groups were comparable in gender, age, severity of sweating and average period of follow-up. All operations were successful with no severe complications or perioperative mortality. A 17.8 +/- 7.9 month follow-up showed that palmar sweating improved in all patients and the effective rate was 100%. Mild moist hands occurred more frequent in group T4 than in group T3 (59.4% vs 25.8%, p < 0.0001). Most involved patients were ′very satisfied′ with this result except for four patients (5.8%) in group T4; incidences of compensatory sweating and over dry hands were both lower in group T4 than in group T3 (56.5% vs 77.4%, p = 0.011 and 1.4% vs 12.9%, p = 0.013, respectively). Moderate compensatory sweating (CS) occurred in 14.5% in group T3 and 2.9% in group T4 (p = 0.017). ′Very satisfied′ rate was higher in group T4 than in group T3 (p < 0.0001) while ′partially satisfied′ rate was comparable between the two groups. Conclusion: T3 and T4 sympathicotomies are both effective for the treatment of PH. T4 sympathicotomy, decreases the side effects but do not compromise the therapeutic effects, and should be the method of choice. (C) 2009 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.

语种英语
WOS记录号WOS:000264971600004
引用统计
被引频次:47[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60298
专题北京大学第二临床医学院_胸外科
北京大学基础医学院
作者单位1.Peking Univ, Dept Thorac Surg, Peoples Hosp, Ctr Thorac Mini Invas Surg, Beijing 100044, Peoples R China
2.Beijing Haidian Hosp, Dept Thorac Surg, Beijing 100080, Peoples R China
推荐引用方式
GB/T 7714
Liu, Yanguo,Yang, Jie,Liu, Jun,et al. Surgical treatment of primary palmar hyperhidrosis: a prospective randomized study comparing T3 and T4 sympathicotomy[J]. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY,2009,35(3):398-402.
APA Liu, Yanguo.,Yang, Jie.,Liu, Jun.,Yang, Fan.,Jiang, Guanchao.,...&Wang, Jun.(2009).Surgical treatment of primary palmar hyperhidrosis: a prospective randomized study comparing T3 and T4 sympathicotomy.EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY,35(3),398-402.
MLA Liu, Yanguo,et al."Surgical treatment of primary palmar hyperhidrosis: a prospective randomized study comparing T3 and T4 sympathicotomy".EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY 35.3(2009):398-402.
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