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学科主题: 临床医学
题名:
Atmospheric pressure cold plasma as an antifungal therapy
作者: Sun, Peng3; Sun, Yi1,2; Wu, Haiyan3; Zhu, Weidong5,6; Lopez, Jose L.5,6; Liu, Wei1,2; Zhang, Jue3,4; Li, Ruoyu1,2; Fang, Jing3,4
刊名: APPLIED PHYSICS LETTERS
发表日期: 2011-01-10
DOI: 10.1063/1.3530434
卷: 98, 期:2
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Physics, Applied
研究领域[WOS]: Physics
关键词[WOS]: BACILLUS-SUBTILIS SPORES ; AIR PLASMA ; DIAPER DERMATITIS ; INACTIVATION ; TEMPERATURE ; BACTERIA ; CANDIDA ; MICROJET
英文摘要:

A microhollow cathode based, direct-current, atmospheric pressure, He/O(2) (2%) cold plasma microjet was used to inactive antifungal resistants Candida albicans, Candida krusei, and Candida glabrata in air and in water. Effective inactivation (>90%) was achieved in 10 min in air and 1 min in water. Antifungal susceptibility tests showed drastic reduction of the minimum inhibitory concentration after plasma treatment. The inactivation was attributed to the reactive oxygen species generated in plasma or in water. Hydroxyl and singlet molecular oxygen radicals were detected in plasma-water system by electron spin resonance spectroscopy. This approach proposed a promising clinical dermatology therapy. (C) 2011 American Institute of Physics. [doi:10.1063/1.3530434]

语种: 英语
所属项目编号: 2007CB935602 ; 2008KR1330 ; FA9550-08-1-0332
项目资助者: Bioelectrics Inc. (U.S.A.) ; China International Science and Technology Cooperation ; U.S. Air Force Office of Scientific Research (AFOSR)
WOS记录号: WOS:000286470800017
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60305
Appears in Collections:北京大学第一临床医学院_期刊论文

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作者单位: 1.St Peters Coll, Ctr Microplasma Sci & Technol, Jersey City, NJ 07306 USA
2.Peking Univ, Res Ctr Med Mycol, Beijing 100034, Peoples R China
3.Peking Univ, Coll Engn, Beijing 100871, Peoples R China
4.St Peters Coll, Dept Appl Sci & Technol, Jersey City, NJ 07306 USA
5.Peking Univ, Dept Dermatol & Venerol, Hosp 1, Beijing 100034, Peoples R China
6.Peking Univ, Acad Adv Interdisciplinary Studies, Beijing 100871, Peoples R China

Recommended Citation:
Sun, Peng,Sun, Yi,Wu, Haiyan,et al. Atmospheric pressure cold plasma as an antifungal therapy[J]. APPLIED PHYSICS LETTERS,2011,98(2).
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