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学科主题临床医学
Atmospheric pressure cold plasma as an antifungal therapy
Sun, Peng3; Sun, Yi1,2; Wu, Haiyan3; Zhu, Weidong5,6; Lopez, Jose L.5,6; Liu, Wei1,2; Zhang, Jue3,4; Li, Ruoyu1,2; Fang, Jing3,4
刊名APPLIED PHYSICS LETTERS
2011-01-10
DOI10.1063/1.3530434
98期:2
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Physics, Applied
研究领域[WOS]Physics
关键词[WOS]BACILLUS-SUBTILIS SPORES ; AIR PLASMA ; DIAPER DERMATITIS ; INACTIVATION ; TEMPERATURE ; BACTERIA ; CANDIDA ; MICROJET
英文摘要

A microhollow cathode based, direct-current, atmospheric pressure, He/O(2) (2%) cold plasma microjet was used to inactive antifungal resistants Candida albicans, Candida krusei, and Candida glabrata in air and in water. Effective inactivation (>90%) was achieved in 10 min in air and 1 min in water. Antifungal susceptibility tests showed drastic reduction of the minimum inhibitory concentration after plasma treatment. The inactivation was attributed to the reactive oxygen species generated in plasma or in water. Hydroxyl and singlet molecular oxygen radicals were detected in plasma-water system by electron spin resonance spectroscopy. This approach proposed a promising clinical dermatology therapy. (C) 2011 American Institute of Physics. [doi:10.1063/1.3530434]

语种英语
WOS记录号WOS:000286470800017
项目编号2007CB935602 ; 2008KR1330 ; FA9550-08-1-0332
资助机构Bioelectrics Inc. (U.S.A.) ; China International Science and Technology Cooperation ; U.S. Air Force Office of Scientific Research (AFOSR)
引用统计
被引频次:39[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60305
专题北京大学第一临床医学院
北京大学第一临床医学院_皮肤性病科
北京大学第三临床医学院_泌尿外科
北京大学口腔医学院_牙周科
作者单位1.St Peters Coll, Ctr Microplasma Sci & Technol, Jersey City, NJ 07306 USA
2.Peking Univ, Res Ctr Med Mycol, Beijing 100034, Peoples R China
3.Peking Univ, Coll Engn, Beijing 100871, Peoples R China
4.St Peters Coll, Dept Appl Sci & Technol, Jersey City, NJ 07306 USA
5.Peking Univ, Dept Dermatol & Venerol, Hosp 1, Beijing 100034, Peoples R China
6.Peking Univ, Acad Adv Interdisciplinary Studies, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Sun, Peng,Sun, Yi,Wu, Haiyan,et al. Atmospheric pressure cold plasma as an antifungal therapy[J]. APPLIED PHYSICS LETTERS,2011,98(2).
APA Sun, Peng.,Sun, Yi.,Wu, Haiyan.,Zhu, Weidong.,Lopez, Jose L..,...&Fang, Jing.(2011).Atmospheric pressure cold plasma as an antifungal therapy.APPLIED PHYSICS LETTERS,98(2).
MLA Sun, Peng,et al."Atmospheric pressure cold plasma as an antifungal therapy".APPLIED PHYSICS LETTERS 98.2(2011).
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