IR@PKUHSC  > 北京大学第一临床医学院
学科主题临床医学
International Association of Diabetes and Pregnancy Study Group criteria is suitable for gestational diabetes mellitus diagnosis: further evidence from China
Wei Yumei1; Yang Huixia1; Zhu Weiwei1; Yang Hongyun2; Li Haixia2; Yan Jie1; Zhang Cuilin3
关键词gestational diabetes mellitus macrosomia cesarean section neonatal hypoglycemia
刊名CHINESE MEDICAL JOURNAL
2014-10-20
DOI10.3760/cma.j.issn.0366-6999.20140898
127期:20页:3553-3556
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal
资助者World Diabetes Foundation ; World Diabetes Foundation
研究领域[WOS]General & Internal Medicine
关键词[WOS]GLUCOSE-TOLERANCE TEST ; WOMEN ; CLASSIFICATION ; HYPERGLYCEMIA ; TESTS ; 75-G
英文摘要

Background The International Association of Diabetes and Pregnancy Study Group (IADPSG) recommended new diagnostic criteria for gestational diabetes mellitus (GDM) after extensive analyses of the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study. Unfortunately, there was no data from mainland of China in this study. We evaluated the feasibility of IADPSG criteria for GDM diagnosis in China.

Methods A large prospective study was conducted. We reviewed medical records of a total of 25 674 pregnant women who underwent GDM screening and diagnosis between January 1, 2005 and December 31, 2012 in the Peking University First Hospital. The prevalence of gestational glucose metabolism abnormalities was calculated according to different cut off values defined by the National Diabetes Data Group (NDDG) or the IADPSG, and the incidence of adverse pregnancy outcomes related to GDM was analyzed.

Results According to the cut off values of NDDG and IADPSG criteria, the prevalence of gestational glucose metabolism abnormalities was 8.4% and 18.9% (P<0.01) respectively, and the prevalence of cesarean section (52.5% vs. 46.0%, P<0.01), macrosomia (7.5% vs. 6.3%, P<0.05), neonatal hypoglycemia (1.6% vs. 1.0%, P<0.01), and perinatal death (0.5% vs. 0.2%, P<0.01); the prevalence was significantly lower when IADPSG criteria were applied. The prevalence of macrosomia, cesarean section, neonatal hypoglycemia, pregnancy induced hypertension, etc. was also higher in the GDM group than in the normal group. The prevalence of cesarean section (62.3%) and nnacrosomia (14.8%) was the highest in untreated mild GDM patients.

Conclusions Our results indicated that treatment/intervention of women with GDM identified by IADPSG criteria was related to significantly lower risk of multiple adverse pregnancy outcomes. Such findings provide support for applying IADPSG criteria in China.

语种英语
所属项目编号WDF10-517
资助者World Diabetes Foundation ; World Diabetes Foundation
WOS记录号WOS:000344724100007
Citation statistics
Cited Times:21[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60306
Collection北京大学第一临床医学院
作者单位1.Peking Univ, Hosp 1, Dept Obstet & Gynecol, Beijing 100034, Peoples R China
2.Peking Univ, Hosp 1, Dept Clin Lab, Beijing 100034, Peoples R China
3.NICHD, Div Epidemiol Stat & Prevent Res, NIH, Rockville, MD 20852 USA
Recommended Citation
GB/T 7714
Wei Yumei,Yang Huixia,Zhu Weiwei,et al. International Association of Diabetes and Pregnancy Study Group criteria is suitable for gestational diabetes mellitus diagnosis: further evidence from China[J]. CHINESE MEDICAL JOURNAL,2014,127(20):3553-3556.
APA Wei Yumei.,Yang Huixia.,Zhu Weiwei.,Yang Hongyun.,Li Haixia.,...&Zhang Cuilin.(2014).International Association of Diabetes and Pregnancy Study Group criteria is suitable for gestational diabetes mellitus diagnosis: further evidence from China.CHINESE MEDICAL JOURNAL,127(20),3553-3556.
MLA Wei Yumei,et al."International Association of Diabetes and Pregnancy Study Group criteria is suitable for gestational diabetes mellitus diagnosis: further evidence from China".CHINESE MEDICAL JOURNAL 127.20(2014):3553-3556.
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