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A convenient four-component one-pot synthesis of 2-amino-1,3,4-thiadiazoles in water
Liu, Peng; Su, Ao-Ze; Wang, Yuan-Qiang; Ge, Ze-Mei; Cheng, Tie-Ming; Li, Run-Tao
关键词2-amino-1, 3, 4-thiadiazole Four-component one-pot reaction Primary amines Carbon disulfide Acyl chloride MCR
刊名MOLECULAR DIVERSITY
2014-11-01
DOI10.1007/s11030-014-9526-6
18期:4页:737-743
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Chemistry, Applied ; Chemistry, Medicinal ; Chemistry, Multidisciplinary
资助者National Natural Science Foundation of China ; National Natural Science Foundation of China
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]CARBONIC-ANHYDRASE INHIBITORS ; 1,3,4-THIADIAZOLE DERIVATIVES ; ANTIPROLIFERATIVE ACTIVITY ; POTENTIAL ANTICONVULSANT ; ANTILEISHMANIAL ACTIVITY ; ANTIINFLAMMATORY AGENTS ; EFFICIENT SYNTHESIS ; IN-VITRO ; 1,2,4-TRIAZOLE ; ANALOGS
英文摘要

A novel four-component one-pot approach for the synthesis of 2-amino-1,3,4-thiadiazoles from primary amines, carbon disulfide, hydrazine, and acyl chlorides has been developed. A series of 5-substituted-2-amino-1,3,4-thiadiazoles were synthesized in medium-to-good yields utilizing this newly developed method.

语种英语
所属项目编号21172011
资助者National Natural Science Foundation of China ; National Natural Science Foundation of China
WOS记录号WOS:000343605000004
Citation statistics
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60318
Collection北京大学药学院
作者单位Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
Recommended Citation
GB/T 7714
Liu, Peng,Su, Ao-Ze,Wang, Yuan-Qiang,et al. A convenient four-component one-pot synthesis of 2-amino-1,3,4-thiadiazoles in water[J]. MOLECULAR DIVERSITY,2014,18(4):737-743.
APA Liu, Peng,Su, Ao-Ze,Wang, Yuan-Qiang,Ge, Ze-Mei,Cheng, Tie-Ming,&Li, Run-Tao.(2014).A convenient four-component one-pot synthesis of 2-amino-1,3,4-thiadiazoles in water.MOLECULAR DIVERSITY,18(4),737-743.
MLA Liu, Peng,et al."A convenient four-component one-pot synthesis of 2-amino-1,3,4-thiadiazoles in water".MOLECULAR DIVERSITY 18.4(2014):737-743.
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