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学科主题: 药学
题名:
A convenient four-component one-pot synthesis of 2-amino-1,3,4-thiadiazoles in water
作者: Liu, Peng; Su, Ao-Ze; Wang, Yuan-Qiang; Ge, Ze-Mei; Cheng, Tie-Ming; Li, Run-Tao
关键词: 2-amino-1, 3, 4-thiadiazole ; Four-component one-pot reaction ; Primary amines ; Carbon disulfide ; Acyl chloride ; MCR
刊名: MOLECULAR DIVERSITY
发表日期: 2014-11-01
DOI: 10.1007/s11030-014-9526-6
卷: 18, 期:4, 页:737-743
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biochemistry & Molecular Biology ; Chemistry, Applied ; Chemistry, Medicinal ; Chemistry, Multidisciplinary
研究领域[WOS]: Biochemistry & Molecular Biology ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]: CARBONIC-ANHYDRASE INHIBITORS ; 1,3,4-THIADIAZOLE DERIVATIVES ; ANTIPROLIFERATIVE ACTIVITY ; POTENTIAL ANTICONVULSANT ; ANTILEISHMANIAL ACTIVITY ; ANTIINFLAMMATORY AGENTS ; EFFICIENT SYNTHESIS ; IN-VITRO ; 1,2,4-TRIAZOLE ; ANALOGS
英文摘要:

A novel four-component one-pot approach for the synthesis of 2-amino-1,3,4-thiadiazoles from primary amines, carbon disulfide, hydrazine, and acyl chlorides has been developed. A series of 5-substituted-2-amino-1,3,4-thiadiazoles were synthesized in medium-to-good yields utilizing this newly developed method.

语种: 英语
所属项目编号: 21172011
项目资助者: National Natural Science Foundation of China
WOS记录号: WOS:000343605000004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60318
Appears in Collections:北京大学药学院_期刊论文

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作者单位: Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

Recommended Citation:
Liu, Peng,Su, Ao-Ze,Wang, Yuan-Qiang,et al. A convenient four-component one-pot synthesis of 2-amino-1,3,4-thiadiazoles in water[J]. MOLECULAR DIVERSITY,2014,18(4):737-743.
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