|Campylobacter enteritis in adult patients with acute diarrhea from 2005 to 2009 in Beijing, China|
|Chen Jie; Sun Xin-ting; Zeng Zheng; Yu Yan-yan|
|关键词||Campylobacter enteritis drug resistance signs and symptoms|
|刊名||CHINESE MEDICAL JOURNAL|
|WOS标题词||Science & Technology|
|类目[WOS]||Medicine, General & Internal|
|研究领域[WOS]||General & Internal Medicine|
|关键词[WOS]||NORTHERN TAIWAN ; SAUDI-ARABIA ; JEJUNI ; INFECTIONS ; RESISTANCE ; EPIDEMIOLOGY ; CHILDREN|
Background There has been a marked global increase in the incidence of human Campylobacter enteritis in recent years. This study investigated the epidemiological and clinical features of Campylobacter enteritis in adult patients suffering from acute diarrhea.
Methods This was a retrospective review of Campylobacter enteritis in adult patients with acute diarrhea presenting at Beijing University First Hospital, Beijing, China, in the summer and autumn (April to October) of 2005 to 2009. The data collected included the species of campylobacter identified, and the age, gender, clinical manifestations and results of laboratory test on stool samples collected from the patients. Campylobacter sensitivity tests to various antimicrobial agents were conducted on 80 specimens. Chi-square tests were applied using SPSS13.0 software and a two-sided P value of < 0.05 was considered statistically significant.
Results Campylobacter spp. isolated from the stool specimens of 142 patients with diarrhea represented 14.9% of all the cases examined. C. jejuni was identified in 127 patients (89.4%) and C. coli in 15 others (10.6%). The infection incidence was highest in the age range of 21-30 years which comprised 21.7% of the total cases examined. Most cases of diarrhea (46 patients) occurred in June. Watery diarrhea (97.2%), abdominal pain (72.5%) and fever (64.8%) were the most common manifestations of enteric campylobacteriosis. Only four patients (2.8%) had bloody diarrhea. The antimicrobial resistance rates were: cefoperazone (100%), levofloxacin (61.3%), gentamicin (12.5%), erythromycin (6.3%), and azithromycin (2.5%).
Conclusions Campylobacter was prevalent among adults with acute diarrhea from 2005 to 2009 in Beijing, China. The large number of those afflicted by the disease warrants the commission of a large multicenter study to determine the extent of enteric campylobacteriosis in this region. Chin Med J 2011;124(10):1508-1512
|作者单位||Peking Univ First Hosp, Dept Infect Dis, Beijing 100034, Peoples R China|
|Chen Jie,Sun Xin-ting,Zeng Zheng,et al. Campylobacter enteritis in adult patients with acute diarrhea from 2005 to 2009 in Beijing, China[J]. CHINESE MEDICAL JOURNAL,2011,124(10):1508-1512.|
|APA||Chen Jie,Sun Xin-ting,Zeng Zheng,&Yu Yan-yan.(2011).Campylobacter enteritis in adult patients with acute diarrhea from 2005 to 2009 in Beijing, China.CHINESE MEDICAL JOURNAL,124(10),1508-1512.|
|MLA||Chen Jie,et al."Campylobacter enteritis in adult patients with acute diarrhea from 2005 to 2009 in Beijing, China".CHINESE MEDICAL JOURNAL 124.10(2011):1508-1512.|