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学科主题: 临床医学
题名:
Evaluation of bilateral cingulum with tractography in patients with Alzheimer′s disease
作者: Xie, S; Xiao, JX; Wang, YH; Wu, HK; Gong, GL; Jiang, XX
关键词: Alzheimer&prime ; s disease ; cingulum bundle ; diffusion tensor imaging
刊名: NEUROREPORT
发表日期: 2005-08-22
卷: 16, 期:12, 页:1275-1278
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Neurosciences
研究领域[WOS]: Neurosciences & Neurology
关键词[WOS]: MILD COGNITIVE IMPAIRMENT ; VOXEL-BASED MORPHOMETRY ; GRAY-MATTER LOSS ; DIFFUSION TENSOR ; HIPPOCAMPAL VOLUME ; BRAIN ; AD
英文摘要:

A fiber-tracking algorithm was used to extract fractional anisotropy of bilateral cingulum bundles in patients with probable Alzheimer′s disease and normal aging controls. In addition, their hippocampal volumes were measured manually. Relative to normal controls, Alzheimer′s disease patients showed a significant reduction of fractional anisotropy and hippocampal volumes. Significant correlation was observed between fractional anisotropy values and volumes of hippocampi and mini-mental state examination scores. This study suggests that lower anisotropy of cingulum bundles is associated with cognitive dysfunction and atrophy of the limbic system.

语种: 英语
WOS记录号: WOS:000231492600005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60381
Appears in Collections:北京大学第一临床医学院_放射治疗科_期刊论文

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作者单位: 1.Peking Univ, Hosp 1, Dept Radiol, Beijing 100034, Peoples R China
2.Peking Univ, Hosp 1, Dept Neurol, Beijing 100034, Peoples R China
3.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100080, Peoples R China

Recommended Citation:
Xie, S,Xiao, JX,Wang, YH,et al. Evaluation of bilateral cingulum with tractography in patients with Alzheimer′s disease[J]. NEUROREPORT,2005,16(12):1275-1278.
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