IR@PKUHSC  > 北京大学第一临床医学院  > 放射治疗科
学科主题临床医学
Evaluation of bilateral cingulum with tractography in patients with Alzheimer′s disease
Xie, S; Xiao, JX; Wang, YH; Wu, HK; Gong, GL; Jiang, XX
关键词Alzheimer&prime s disease cingulum bundle diffusion tensor imaging
刊名NEUROREPORT
2005-08-22
16期:12页:1275-1278
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Neurosciences
研究领域[WOS]Neurosciences & Neurology
关键词[WOS]MILD COGNITIVE IMPAIRMENT ; VOXEL-BASED MORPHOMETRY ; GRAY-MATTER LOSS ; DIFFUSION TENSOR ; HIPPOCAMPAL VOLUME ; BRAIN ; AD
英文摘要

A fiber-tracking algorithm was used to extract fractional anisotropy of bilateral cingulum bundles in patients with probable Alzheimer′s disease and normal aging controls. In addition, their hippocampal volumes were measured manually. Relative to normal controls, Alzheimer′s disease patients showed a significant reduction of fractional anisotropy and hippocampal volumes. Significant correlation was observed between fractional anisotropy values and volumes of hippocampi and mini-mental state examination scores. This study suggests that lower anisotropy of cingulum bundles is associated with cognitive dysfunction and atrophy of the limbic system.

语种英语
WOS记录号WOS:000231492600005
引用统计
被引频次:57[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60381
专题北京大学第一临床医学院_放射治疗科
作者单位1.Peking Univ, Hosp 1, Dept Radiol, Beijing 100034, Peoples R China
2.Peking Univ, Hosp 1, Dept Neurol, Beijing 100034, Peoples R China
3.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100080, Peoples R China
推荐引用方式
GB/T 7714
Xie, S,Xiao, JX,Wang, YH,et al. Evaluation of bilateral cingulum with tractography in patients with Alzheimer′s disease[J]. NEUROREPORT,2005,16(12):1275-1278.
APA Xie, S,Xiao, JX,Wang, YH,Wu, HK,Gong, GL,&Jiang, XX.(2005).Evaluation of bilateral cingulum with tractography in patients with Alzheimer′s disease.NEUROREPORT,16(12),1275-1278.
MLA Xie, S,et al."Evaluation of bilateral cingulum with tractography in patients with Alzheimer′s disease".NEUROREPORT 16.12(2005):1275-1278.
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