|Prevalence, awareness and treatment of chronic kidney disease among middle-aged and elderly: The China Health and Retirement Longitudinal Study|
|Wang, Shengfeng1; Chen, Ru1; Liu, Qing2; Shu, Zheng1; Zhan, Siyan1; Li, Liming1|
|关键词||Awareness Chronic Kidney Disease Ckd-epi Egfrcr-cys Equation Middle-aged And Elderly Prevalence Treatment|
|WOS标题词||Science & Technology|
|类目[WOS]||Urology & Nephrology|
|研究领域[WOS]||Urology & Nephrology|
|关键词[WOS]||Glomerular-filtration-rate ; Kdoqi Ckd Guidelines ; Cystatin c ; Population ; Hypertension ; Adults ; Prevention ; Cohort ; Metaanalysis ; Creatinine|
AimTo provide reliable estimates of the prevalence, awareness, and treatment of chronic kidney disease (CKD), and their distribution and related influencing factors in middle-aged and elderly population in China.
MethodsA cross-sessional survey called the China Health and Retirement Longitudinal Study (CHARLS) was conducted in 2011-2012 in Chinese people aged 45 years or older. This was to evaluate the prevalence of CKD, disease awareness compared to other chronic diseases in the population, and whether they were being treated for their CKD. Estimated GFR (eGFR) was calculated using the Chronic Kidney Disease Epidemiology Collaboration eGFR creatinine-cystatin C (eGFRcreat-cys) equation. CKD was defined as eGFR less than 60mL/min per 1.73m(2). Multivariable logistic regressions were used to estimate odds ratios (ORs) for the risk factors.
ResultsThe overall prevalence of CKD was 11.5% (95%CI: 10.1%approximate to 12.8%). It was higher in urban than rural population (13.0% vs 10.0%, P<0.05). Among all patients with CKD, only 8.7% were aware of the diagnosis. 4.9% of the patients were receiving treatment. The proportion of those aware of their condition and those who were treated decreased with age in both sexes. Of those aware (8.9%), 55.9% were treated. 31.4% of the treated patients took Chinese traditional medicine.
ConclusionsThere is a surprising prevalence of CKD in the Chinese middle-aged and elderly population, with disproportionately low awareness and treatment. A comprehensive strategy toward prevention, screening, treatment and control of CKD is needed to slow the epidemic of CKD.
|资助机构||PhD Programs Foundation of Ministry of Education of China|
|作者单位||1.Peking Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Hlth Sci Ctr, Beijing 100191, Peoples R China|
2.Brown Univ, Dept Epidemiol, ScM, Sch Publ Hlth, Providence, RI 02912 USA
|Wang, Shengfeng,Chen, Ru,Liu, Qing,et al. Prevalence, awareness and treatment of chronic kidney disease among middle-aged and elderly: The China Health and Retirement Longitudinal Study[J]. NEPHROLOGY,2015,20(7):474-484.|
|APA||Wang, Shengfeng,Chen, Ru,Liu, Qing,Shu, Zheng,Zhan, Siyan,&Li, Liming.(2015).Prevalence, awareness and treatment of chronic kidney disease among middle-aged and elderly: The China Health and Retirement Longitudinal Study.NEPHROLOGY,20(7),474-484.|
|MLA||Wang, Shengfeng,et al."Prevalence, awareness and treatment of chronic kidney disease among middle-aged and elderly: The China Health and Retirement Longitudinal Study".NEPHROLOGY 20.7(2015):474-484.|