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8-hydroxyguanine, a product from damaged DNA can be used in the DNA salvage pathways
Zeng, HH; Choi, JY; Chung, MH
关键词8-hydroxyguanine metabolic reaction DNA salvage pathway
刊名CHINESE CHEMICAL LETTERS
2003-05-01
14期:5页:529-532
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]GENE
英文摘要

The metabolic mechanism of 8-hydroxyguanine (8-OHGua) is so far unknown, however it is known to function in the mutagenic events in biological systems. In the present study, the metabolic processes is investigated by the reaction of 8-OHGua with PRPP catalyzed by HGPRT and Mg(II). The evidence shows that the interaction between 8-OHGua and the enzyme is indeed taken place and 8-OHGMP is formed.

语种英语
WOS记录号WOS:000183628800030
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60392
专题北京大学药学院
作者单位1.Seoul Natl Univ, Coll Med, Dept Pharmacol, Chongno Gu, Seoul 110744, South Korea
2.Peking Univ, Sch Pharmaceut Sci, Beijing 100083, Peoples R China
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GB/T 7714
Zeng, HH,Choi, JY,Chung, MH. 8-hydroxyguanine, a product from damaged DNA can be used in the DNA salvage pathways[J]. CHINESE CHEMICAL LETTERS,2003,14(5):529-532.
APA Zeng, HH,Choi, JY,&Chung, MH.(2003).8-hydroxyguanine, a product from damaged DNA can be used in the DNA salvage pathways.CHINESE CHEMICAL LETTERS,14(5),529-532.
MLA Zeng, HH,et al."8-hydroxyguanine, a product from damaged DNA can be used in the DNA salvage pathways".CHINESE CHEMICAL LETTERS 14.5(2003):529-532.
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