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学科主题: 临床医学
题名:
Application of T2* measurement on gradient echo T2*-weighted imaging in differential diagnosis of intracranial hemorrhage and calcification
作者: Liu Lan-xiang1; Yi Hui-ling1; Han Hong-bin2; Qi Xi-ming1
关键词: intracranial hemorrhage ; calcification ; differential diagnosis ; T2*value ; T2*-weighted imaging
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2012-06-20
DOI: 10.3760/cma.j.issn.0366-6999.2012.12.005
卷: 125, 期:12, 页:2104-2108
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: ACUTE SUBARACHNOID HEMORRHAGE ; MAGNETIC-RESONANCE ; MRI
英文摘要:

Background Differential diagnosis of intracranial hemorrhage and calcification is a common problem encountered in clinical imaging diagnosis. The purpose of this study was to investigate the feasibility of T2* measurement on gradient echo (GRE) T2*-weighted imaging (T2*WI) in differential diagnosis of intracranial hemorrhage and calcification.

Methods Thirty-eight hemorrhagic foci in 18 patients and 11 calcification foci in seven patients were included in this study. The diagnosis of hemorrhage and calcification was confirmed in all cases with enhanced T2* weighted angiography (ESWAN) magnetic resonance imaging (MRI) and CT respectively. The significance for the difference of T2* value between the central and peripheral areas of hemorrhage and calcification lesions was tested with univariate analysis of variance.

Results The detection rate of GRE T2*WI on intracranial hemorrhage was 1.9-fold higher than that of CT, especially for the hemorrhage in the brainstem and cerebellum. However, GRE T2*)All was far less sensitive to calcification than CT. There was a significant difference in the T2* value between the central area of hemorrhage and calcification (P <0.001), though no difference in the T2* value was obtained between the peripheral area of hemorrhage and calcification (P >0.05).

Conclusions Quantitative measurement of T2* value on GRE T2*WI with a single MRI examination provides a fast, convenient, and effective means in differential diagnosis between intracranial hemorrhage and calcification, which may thus reduce the medical cost and save precious time for clinical management. Chin Med J 2012;125(12):2104-2108

语种: 英语
WOS记录号: WOS:000306382400005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60396
Appears in Collections:北京大学第三临床医学院_放射科_期刊论文

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作者单位: 1.Qinhuangdao Municipal 1 Hosp, Dept Magnet Resonance Imaging, Qinhuangdao 066000, Hebei, Peoples R China
2.Peking Univ, Dept Radiol, Hosp 3, Beijing 100191, Peoples R China

Recommended Citation:
Liu Lan-xiang,Yi Hui-ling,Han Hong-bin,et al. Application of T2* measurement on gradient echo T2*-weighted imaging in differential diagnosis of intracranial hemorrhage and calcification[J]. CHINESE MEDICAL JOURNAL,2012,125(12):2104-2108.
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