IR@PKUHSC  > 北京大学基础医学院  > 心血管所
学科主题基础医学
Recent advances of dendrimers in delivery of genes and drugs
Gao, Yu1; Gao, Ge2,3; He, Yun1; Liu, Taole1; Qi, Rong1
关键词dendrimer delivery of dene delivery of drug DNA/RNA PAMAM PEI PPI
刊名MINI-REVIEWS IN MEDICINAL CHEMISTRY
2008-08-01
8期:9页:889-900
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Chemistry, Medicinal
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]OVARIAN TUMOR XENOGRAFTS ; POLYAMIDOAMINE DENDRIMERS ; IN-VITRO ; FOLATE-RECEPTOR ; PAMAM DENDRIMERS ; PLASMID DNA ; BLOCK-COPOLYMER ; GLYCOL)-BLOCK-POLY(L-LYSINE) DENDRIMER ; POLYPROPYLENIMINE DENDRIMERS ; STARBURST DENDRIMERS
英文摘要

Dendrimers as a new kind of polymer have been studied for medical applications mainly in two aspects: drug delivery and gene delivery. The unique characteristics, such as uniformity, monodispersity and the ability to functionalize their terminal groups with various targeting agents distinguish them as versatile carriers. In the paper the recent advances of dendrimer in gene transfer vehicles and drug delivery are separately reviewed. These advances illustrate the direction of the future development of dendrimers.

语种英语
WOS记录号WOS:000259506300004
项目编号30500197
资助机构National Natural Science Foundation of China
引用统计
被引频次:42[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60444
专题北京大学基础医学院_心血管所
作者单位1.Jilin Univ, MacDiarmid Lab, Changchun 130021, Peoples R China
2.Jilin Univ, Coll Chem, Changchun 130021, Peoples R China
3.Peking Univ, Inst Cardiovasc Sci, Beijing 100083, Peoples R China
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GB/T 7714
Gao, Yu,Gao, Ge,He, Yun,et al. Recent advances of dendrimers in delivery of genes and drugs[J]. MINI-REVIEWS IN MEDICINAL CHEMISTRY,2008,8(9):889-900.
APA Gao, Yu,Gao, Ge,He, Yun,Liu, Taole,&Qi, Rong.(2008).Recent advances of dendrimers in delivery of genes and drugs.MINI-REVIEWS IN MEDICINAL CHEMISTRY,8(9),889-900.
MLA Gao, Yu,et al."Recent advances of dendrimers in delivery of genes and drugs".MINI-REVIEWS IN MEDICINAL CHEMISTRY 8.9(2008):889-900.
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