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学科主题: 临床医学
题名:
Fibrous Dysplasia of the Mobile Spine Report of 8 Cases and Review of the Literature
作者: Wu, Feng Liang1; Jiang, Liang1; Liu, Chen2; Yang, Shao Min3; Wei, Feng1; Dang, Lei1; Liu, Xiao Guang1; Liu, Zhong Jun1
关键词: fibrous dysplasia ; mobile spine ; treatment ; vertebroplasty
刊名: SPINE
发表日期: 2013-11-01
DOI: 10.1097/BRS.0b013e3182a8cc05
卷: 38, 期:23, 页:2016-2022
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology ; Orthopedics
研究领域[WOS]: Neurosciences & Neurology ; Orthopedics
关键词[WOS]: OF-THE-LITERATURE ; CORE NEEDLE-BIOPSY ; THORACIC SPINE ; CERVICAL-SPINE ; LUMBAR SPINE ; INTRAVENOUS PAMIDRONATE ; BONE ; FRACTURE ; CT ; COMPLICATION
英文摘要:

Study Design. Eight cases of fibrous dysplasia (FD) of the mobile spine treated surgically at the same center were retrospectively reviewed.

Objective. The study focuses on the issues concerning the diagnosis of FD and the outcome of conventional surgical techniques (resection or curettage) and vertebroplasty in the treatment of spinal FD lesions.

Summary of Background Data. Surgical excision or curettage is considered the standard treatment of spinal FD, whereas vertebroplasty is also performed occasionally.

Methods. Between January 2005 and October 2010, 8 consecutive patients with spinal FD underwent conventional surgery (6 cases) or combined with vertebroplasty (2 cases). Before surgery, 4 patients underwent percutaneous computed tomography-guided biopsy, whereas 3 had incorrect histopathological diagnosis. In each of the 8 cases, the final pathological diagnosis was established after their open surgery.

Results. Pain relief was observed postoperatively in all patients. Three patients with neurological impairment became symptom-free after surgery. No cement extravasation was observed. Screw loosening and allograft resorption were observed in 1 case each. Signs of radiological improvement (filling of lytic lesions or thickening of the bone cortex surrounding the lesions) were not detected in any case.

Conclusion. The radiological features of spinal FD may be atypical. The rate of correct preoperative pathological diagnosis by computed tomography-guided biopsy was low for patients with suspected spinal FD. Vertebroplasty is probably a valuable therapeutic option for spinal FD with pathological fractures. Limited decompression and stability with vertebroplasty might be recommended for patients with neurological deficits.

语种: 英语
WOS记录号: WOS:000330376800017
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60503
Appears in Collections:北京大学第三临床医学院_骨科_期刊论文

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作者单位: 1.Peking Univ, Hosp 3, Dept Orthopaed, Beijing 100191, Peoples R China
2.Peking Univ, Hosp 3, Dept Radiol, Beijing 100191, Peoples R China
3.Peking Univ, Hlth Sci Ctr, Dept Pathol, Beijing 100191, Peoples R China

Recommended Citation:
Wu, Feng Liang,Jiang, Liang,Liu, Chen,et al. Fibrous Dysplasia of the Mobile Spine Report of 8 Cases and Review of the Literature[J]. SPINE,2013,38(23):2016-2022.
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