IR@PKUHSC  > 北京大学第三临床医学院  > 骨科
学科主题临床医学
Fibrous Dysplasia of the Mobile Spine Report of 8 Cases and Review of the Literature
Wu, Feng Liang1; Jiang, Liang1; Liu, Chen2; Yang, Shao Min3; Wei, Feng1; Dang, Lei1; Liu, Xiao Guang1; Liu, Zhong Jun1
关键词fibrous dysplasia mobile spine treatment vertebroplasty
刊名SPINE
2013-11-01
DOI10.1097/BRS.0b013e3182a8cc05
38期:23页:2016-2022
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Clinical Neurology ; Orthopedics
研究领域[WOS]Neurosciences & Neurology ; Orthopedics
关键词[WOS]OF-THE-LITERATURE ; CORE NEEDLE-BIOPSY ; THORACIC SPINE ; CERVICAL-SPINE ; LUMBAR SPINE ; INTRAVENOUS PAMIDRONATE ; BONE ; FRACTURE ; CT ; COMPLICATION
英文摘要

Study Design. Eight cases of fibrous dysplasia (FD) of the mobile spine treated surgically at the same center were retrospectively reviewed.

Objective. The study focuses on the issues concerning the diagnosis of FD and the outcome of conventional surgical techniques (resection or curettage) and vertebroplasty in the treatment of spinal FD lesions.

Summary of Background Data. Surgical excision or curettage is considered the standard treatment of spinal FD, whereas vertebroplasty is also performed occasionally.

Methods. Between January 2005 and October 2010, 8 consecutive patients with spinal FD underwent conventional surgery (6 cases) or combined with vertebroplasty (2 cases). Before surgery, 4 patients underwent percutaneous computed tomography-guided biopsy, whereas 3 had incorrect histopathological diagnosis. In each of the 8 cases, the final pathological diagnosis was established after their open surgery.

Results. Pain relief was observed postoperatively in all patients. Three patients with neurological impairment became symptom-free after surgery. No cement extravasation was observed. Screw loosening and allograft resorption were observed in 1 case each. Signs of radiological improvement (filling of lytic lesions or thickening of the bone cortex surrounding the lesions) were not detected in any case.

Conclusion. The radiological features of spinal FD may be atypical. The rate of correct preoperative pathological diagnosis by computed tomography-guided biopsy was low for patients with suspected spinal FD. Vertebroplasty is probably a valuable therapeutic option for spinal FD with pathological fractures. Limited decompression and stability with vertebroplasty might be recommended for patients with neurological deficits.

语种英语
WOS记录号WOS:000330376800017
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60503
Collection北京大学第三临床医学院_骨科
作者单位1.Peking Univ, Hosp 3, Dept Orthopaed, Beijing 100191, Peoples R China
2.Peking Univ, Hosp 3, Dept Radiol, Beijing 100191, Peoples R China
3.Peking Univ, Hlth Sci Ctr, Dept Pathol, Beijing 100191, Peoples R China
Recommended Citation
GB/T 7714
Wu, Feng Liang,Jiang, Liang,Liu, Chen,et al. Fibrous Dysplasia of the Mobile Spine Report of 8 Cases and Review of the Literature[J]. SPINE,2013,38(23):2016-2022.
APA Wu, Feng Liang.,Jiang, Liang.,Liu, Chen.,Yang, Shao Min.,Wei, Feng.,...&Liu, Zhong Jun.(2013).Fibrous Dysplasia of the Mobile Spine Report of 8 Cases and Review of the Literature.SPINE,38(23),2016-2022.
MLA Wu, Feng Liang,et al."Fibrous Dysplasia of the Mobile Spine Report of 8 Cases and Review of the Literature".SPINE 38.23(2013):2016-2022.
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