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学科主题: 临床医学
题名:
Effect of multidisciplinary team treatment on outcomes of patients with gastrointestinal malignancy
作者: Du, Chang-Zheng1; Li, Jie2; Cai, Yong3; Sun, Ying-Shi4; Xue, Wei-Cheng5; Gu, Jin1
关键词: Multidisciplinary team ; Rectal cancer ; Neoadjuvant radiotherapy ; Prognosis
刊名: WORLD JOURNAL OF GASTROENTEROLOGY
发表日期: 2011-04-21
DOI: 10.3748/wjg.v17.i15.2013
卷: 17, 期:15, 页:2013-2018
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Gastroenterology & Hepatology
研究领域[WOS]: Gastroenterology & Hepatology
关键词[WOS]: ADVANCED COLORECTAL-CANCER ; LOW RECTAL-CANCER ; PREOPERATIVE RADIOTHERAPY ; SPHINCTER PRESERVATION ; PROGNOSTIC-FACTORS ; MANAGEMENT ; SURVIVAL ; MARGINS ; SURGERY ; IMPACT
英文摘要:

AIM: To evaluate the effect of multidisciplinary team (MDT) treatment modality on outcomes of patients with gastrointestinal malignancy in China.

METHODS: Data about patients with gastric and colorectal cancer treated in our center during the past 10 years were collected and divided into two parts. Part 1 consisted of the data collected from 516 consecutive complicated cases discussed at MDT meetings in Peking University School of Oncology (PKUSO) from December 2005 to July 2009. Part 2 consisted of the data collected from 263 consecutive cases of resectable locally advanced rectal cancer from January 2001 to January 2005. These 263 patients were divided into neoadjuvant therapy (NT) group and control group. Patients in NT group received MDT treatment, namely neoadjuvant therapy + surgery + postoperative adjuvant therapy. Patients in control group underwent direct surgery + postoperative adjuvant therapy. The outcomes in two groups were compared.

RESULTS: The treatment strategy was altered after discussed at MDT meeting in 76.81% of gastric cancer patients and in 58.33% of colorectal cancer patients before operation. The sphincter-preservation and local control of tumor were better in NT group than in control group. The 5-year overall survival rate was also higher in NT group than in control group (77.23% vs 69.75%, P = 0.049).

CONCLUSION: MDT treatment modality can significantly improve the outcomes of patients with gastrointestinal malignancy in China. (C) 2011 Baishideng. All rights reserved.

语种: 英语
WOS记录号: WOS:000290179000012
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60526
Appears in Collections:北京大学临床肿瘤学院_胃肠肿瘤中心_期刊论文

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作者单位: 1.Peking Univ, Dept Colorectal Surg, Sch Oncol, Beijing 100142, Peoples R China
2.Peking Univ, Dept Med Oncol, Sch Oncol, Beijing 100142, Peoples R China
3.Peking Univ, Dept Radiotherapy, Sch Oncol, Beijing 100142, Peoples R China
4.Peking Univ, Dept Radiol, Sch Oncol, Beijing 100142, Peoples R China
5.Peking Univ, Dept Pathol, Sch Oncol, Beijing 100142, Peoples R China

Recommended Citation:
Du, Chang-Zheng,Li, Jie,Cai, Yong,et al. Effect of multidisciplinary team treatment on outcomes of patients with gastrointestinal malignancy[J]. WORLD JOURNAL OF GASTROENTEROLOGY,2011,17(15):2013-2018.
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