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学科主题: 临床医学
题名:
Decompression alone versus decompression with instrumented fusion for young patients with single-level lumbar disc herniation: a short-term prospective comparative study
作者: Sun Zhuoran; Li Weishi; Chen Zhongqiang; Guo Zhaoqing; Qi Qiang; Zeng Yan; Sun Chuiguo; Liu Ning
关键词: young patients ; single level ; lumbar disc herniation ; decompression alone ; prospective study
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2014-06-05
DOI: 10.3760/cma.j.issn.0366-6999.20122204
卷: 127, 期:11, 页:2037-2042
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: ADJACENT SEGMENT DEGENERATION ; SPINAL-FUSION ; FOLLOW-UP ; RISK-FACTORS ; DISKECTOMY ; EXCISION ; OUTCOMES ; LAMINECTOMY ; SURGERY ; DISCECTOMY
英文摘要:

Background For young patients, the surgical method for lumbar disc herniation remains controversial. The aim of this study was to prospectively determine the short-term clinical outcome after surgery for young patients with lumbar disc herniation.

Methods In this prospective comparative study between April 2010 and August 2011, a total of 80 patients underwent primary surgery at a single level for lumbar disc herniation. The patients were divided into two groups: decompression alone and decompression with instrumented fusion. An independent examiner clinically evaluated the patients at preoperation and at 1, 3, 6, and 12 months after surgery. The patients filled out the instruments for back and leg pain using a Visual Analog Scale (VAS), Oswestry Low Back Pain Disability Questionnaire (ODD, and Japanese Orthopaedic Association (JOA) scores. The differences between the two groups were analyzed.

Results The mean age of all the patients at the time of surgery was 33.7 years. Of the 80 patients, 38 patients underwent decompression alone and 42 patients underwent posterior lumbar interbody fusion. Increasing complexity of surgery was associated with a longer surgery time, greater blood loss, and a longer hospital stay after surgery. Both methods of surgery independently improved outcomes compared with baseline status based on VAS, ODI, and JOA scores (P <0.05), and no significant differences were found between the two groups at most of the measuring points in time, although patients with decompression alone had a higher JOA score (P=0.016) and higher JOA recovery rate (P=0.010) at the 3-month follow-up.

Conclusions The short-term results of our study showed that both methods of surgery obtained effective clinical outcomes, but decompression alone had some advantages (shorter surgery time, less blood loss, shorter hospital stay, and lower cost) compared with decompression with instrumented fusion. Young patients with decompression alone could achieve great physical function earlier.

语种: 英语
WOS记录号: WOS:000339034300008
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60608
Appears in Collections:北京大学第三临床医学院_骨科_期刊论文

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作者单位: Peking Univ, Hosp 3, Dept Orthopaed, Beijing 100191, Peoples R China

Recommended Citation:
Sun Zhuoran,Li Weishi,Chen Zhongqiang,et al. Decompression alone versus decompression with instrumented fusion for young patients with single-level lumbar disc herniation: a short-term prospective comparative study[J]. CHINESE MEDICAL JOURNAL,2014,127(11):2037-2042.
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