IR@PKUHSC  > 北京大学精神卫生研究所
学科主题精神卫生
Association study between interleukin-1 beta gene (IL-1 beta) and schizophrenia
Yang, HZ; Si, TM; Ling, YS; Ruan, Y; Han, YH; Wang, XL; Zhou, M; Zhang, DR; Zhang, HY; Kong, QM; Liu, C; Lia, XN; Yu, YQ; Liu, SZ; Shu, L; Ma, DL; Wei, J; Zhang, D
关键词schizophrenia interleukin-1 beta (IL-1 beta) polymorphism the transmission disequilibrium test (TDT)
刊名LIFE SCIENCES
2003-05-16
DOI10.1016/S0024-3205(03)00248-0
72期:26页:3017-3021
收录类别SCI ; SSCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, Research & Experimental ; Pharmacology & Pharmacy
研究领域[WOS]Research & Experimental Medicine ; Pharmacology & Pharmacy
关键词[WOS]CYTOKINES ; BRAIN
英文摘要

An increasing amount of evidence suggests that the pathophysiology of schizophrenia is associated with the abnormal immune system, and cytokines may be important in schizophrenia. Among these cytokines, interleukin-1beta may play a role in the pathogenesis of the disease. In the present study, we investigated the genetic association between a TaqI polymorphism in interleukin-1beta gene (IL-1beta) and schizophrenia by restriction fragment length polymorphism, (RFLP) analysis among 132 Chinese families of Han descent. The transmission disequilibrium. test (TDT) did not demonstrate an allelic association with schizophrenia. Our results suggested that the TaqI polymorphism. in IL-1beta gene might not confer increased susceptibility for schizophrenia. (C) 2003 Elsevier Science Inc. All rights reserved.

语种英语
WOS记录号WOS:000182522400008
引用统计
被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60625
专题北京大学精神卫生研究所
作者单位1.Peking Univ, Inst Mental Hlth, Beijing 100083, Peoples R China
2.Jilin Univ, Ctr Genom Med, Changchun 130021, Peoples R China
3.Peking Univ, Ctr Human Dis Genom, Beijing 100083, Peoples R China
推荐引用方式
GB/T 7714
Yang, HZ,Si, TM,Ling, YS,et al. Association study between interleukin-1 beta gene (IL-1 beta) and schizophrenia[J]. LIFE SCIENCES,2003,72(26):3017-3021.
APA Yang, HZ.,Si, TM.,Ling, YS.,Ruan, Y.,Han, YH.,...&Zhang, D.(2003).Association study between interleukin-1 beta gene (IL-1 beta) and schizophrenia.LIFE SCIENCES,72(26),3017-3021.
MLA Yang, HZ,et al."Association study between interleukin-1 beta gene (IL-1 beta) and schizophrenia".LIFE SCIENCES 72.26(2003):3017-3021.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Yang, HZ]的文章
[Si, TM]的文章
[Ling, YS]的文章
百度学术
百度学术中相似的文章
[Yang, HZ]的文章
[Si, TM]的文章
[Ling, YS]的文章
必应学术
必应学术中相似的文章
[Yang, HZ]的文章
[Si, TM]的文章
[Ling, YS]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。