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Effect of marine collagen peptides on long bone development in growing rats
Xu, YaJun; Han, XiaoLong; Li, Yong
关键词marine collagen peptides bone turnover bone mineral density bone biomechanics
刊名JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
2010-07-01
DOI10.1002/jsfa.3972
90期:9页:1485-1491
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Agriculture, Multidisciplinary ; Chemistry, Applied ; Food Science & Technology
资助者National Natural Science Foundation of China ; National Key Technology RD Program ; National Natural Science Foundation of China ; National Key Technology RD Program
研究领域[WOS]Agriculture ; Chemistry ; Food Science & Technology
关键词[WOS]SALMON ONCORHYNCHUS-KETA ; FOOD-DERIVED PEPTIDES ; MINERAL DENSITY ; FAT MASS ; CASEIN PHOSPHOPEPTIDES ; MECHANICAL-PROPERTIES ; RELATIVE CONTRIBUTION ; PREMENOPAUSAL WOMEN ; AGE ; MILK
英文摘要

BACKGROUND: Nutritional factors play an important role in skeletal development during growth. However, the absorption rates of many bone-related minerals are relatively low from traditional diets, especially for people in Asia and Africa. In the present study, the effect of marine collagen peptides (MCP) derived from chum salmon (Oncorhynchus keta) skin on the development of femurs in growing rats of both sexes was investigated.

RESULTS: MCP supplementation could increase the size, mineral density, dry weight, ash weight, content of most minerals and both stiffness and toughness of femurs in male growing rats. However, such effects were milder in female rats. The reported increase in mineral density was likely to be related to increased osteoblast activity rather than a decreased rate of bone resorption, as an increase in serum osteocalcin and bone-specific alkaline phosphatase content was observed, but no significant difference in serum N-terminal telopeptide of type I collagen compared with control was found.

CONCLUSION: MCP supplementation could promote the development of long bones in growing male rats. (C) 2010 Society of Chemical Industry

语种英语
所属项目编号CO30103 ; 2006BAK02A07-6
资助者National Natural Science Foundation of China ; National Key Technology RD Program ; National Natural Science Foundation of China ; National Key Technology RD Program
WOS记录号WOS:000279414500015
Citation statistics
Cited Times:18[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60672
Collection北京大学公共卫生学院
作者单位Peking Univ, Hlth Sci Ctr, Dept Food Hyg & Nutr, Sch Publ Hlth, Beijing 100191, Peoples R China
Recommended Citation
GB/T 7714
Xu, YaJun,Han, XiaoLong,Li, Yong. Effect of marine collagen peptides on long bone development in growing rats[J]. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,2010,90(9):1485-1491.
APA Xu, YaJun,Han, XiaoLong,&Li, Yong.(2010).Effect of marine collagen peptides on long bone development in growing rats.JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,90(9),1485-1491.
MLA Xu, YaJun,et al."Effect of marine collagen peptides on long bone development in growing rats".JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE 90.9(2010):1485-1491.
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