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学科主题临床医学
Chemical lumbar sympathectomy in the treatment of idiopathic livedo reticularis
Wang, Wen-Hui1; Zhang, Long2; Li, Xuan2; Zhao, Jun2; Zhuang, Jin-man2; Dong, Guo-Xiang2
刊名JOURNAL OF VASCULAR SURGERY
2015-10-01
DOI10.1016/j.jvs.2015.04.419
62期:4页:1018-1022
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Surgery ; Peripheral Vascular Disease
研究领域[WOS]Surgery ; Cardiovascular System & Cardiology
关键词[WOS]COMPLICATION
英文摘要

Objective: Livedo reticularis (LR) is a reticulated discoloration of the skin, particularly on lower extremities. Few treatment options are reported. This study investigated the efficacy and safety of chemical lumbar sympathectomy (CLS) in idiopathic LR. The key technique points of CLS are also illustrated in detail.

Methods: Patients with idiopathic LR with a strong desire for treatment were recruited during a 2.5-year period. L3-4 CLSs were performed with 5% phenol (2 mL) in each injection site. The needle tip extends to approximately one-third of the vertical dividing line of the vertebral body. The contrast along the psoas muscle fibers indicates targeting on gray rami communicans instead of the sympathetic trunk. The primary efficacy variable was achieving "clear or almost clear" of LR lesions staying >1 hour in a 24 degrees C air-conditioned room. Safety assessments included monitoring and recording of all adverse events and tolerability to treatment. The follow-up period was 2.5 to 4.7 years.

Results: Ten women (median age, 22 years) were enrolled. Seven patients achieved "clear or almost clear" of LR lesions after CLS. The postoperative skin surface temperature increase was 7.4 degrees C +/- 2.6 degrees C. Two patients achieved "major partially resolved," and one patient achieved "minor partially resolved." Two of the seven with "clear or almost clear" results reported recurrence <= 1 year during the follow-up, CLS was repeated, and they then achieved "clear or almost clear" again. Two patients reported mild pain localized to the thigh area, which resolved spontaneously by the second day.

Conclusions: This study showed CLS provides a valid option for the treatment of idiopathic LR. The efficacy of CLS can be long-lasting, and CLS can be repeated if LR recurs. Targeting at gray rami communicans, rather than the sympathetic trunk, is comparably effective and safer for sympathetic interruption.

语种英语
WOS记录号WOS:000361885800028
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60684
专题北京大学第三临床医学院_皮肤科
北京大学第三临床医学院_介入血管外科
作者单位1.Peking Univ, Hosp 3, Dept Dermatol, Beijing 100191, Peoples R China
2.Peking Univ, Hosp 3, Dept Intervent Radiol & Vasc Surg, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Wang, Wen-Hui,Zhang, Long,Li, Xuan,et al. Chemical lumbar sympathectomy in the treatment of idiopathic livedo reticularis[J]. JOURNAL OF VASCULAR SURGERY,2015,62(4):1018-1022.
APA Wang, Wen-Hui,Zhang, Long,Li, Xuan,Zhao, Jun,Zhuang, Jin-man,&Dong, Guo-Xiang.(2015).Chemical lumbar sympathectomy in the treatment of idiopathic livedo reticularis.JOURNAL OF VASCULAR SURGERY,62(4),1018-1022.
MLA Wang, Wen-Hui,et al."Chemical lumbar sympathectomy in the treatment of idiopathic livedo reticularis".JOURNAL OF VASCULAR SURGERY 62.4(2015):1018-1022.
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