北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第三临床医学院  > 皮肤科  > 期刊论文
学科主题: 临床医学
题名:
Chemical lumbar sympathectomy in the treatment of idiopathic livedo reticularis
作者: Wang, Wen-Hui1; Zhang, Long2; Li, Xuan2; Zhao, Jun2; Zhuang, Jin-man2; Dong, Guo-Xiang2
刊名: JOURNAL OF VASCULAR SURGERY
发表日期: 2015-10-01
DOI: 10.1016/j.jvs.2015.04.419
卷: 62, 期:4, 页:1018-1022
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Surgery ; Peripheral Vascular Disease
研究领域[WOS]: Surgery ; Cardiovascular System & Cardiology
关键词[WOS]: COMPLICATION
英文摘要:

Objective: Livedo reticularis (LR) is a reticulated discoloration of the skin, particularly on lower extremities. Few treatment options are reported. This study investigated the efficacy and safety of chemical lumbar sympathectomy (CLS) in idiopathic LR. The key technique points of CLS are also illustrated in detail.

Methods: Patients with idiopathic LR with a strong desire for treatment were recruited during a 2.5-year period. L3-4 CLSs were performed with 5% phenol (2 mL) in each injection site. The needle tip extends to approximately one-third of the vertical dividing line of the vertebral body. The contrast along the psoas muscle fibers indicates targeting on gray rami communicans instead of the sympathetic trunk. The primary efficacy variable was achieving "clear or almost clear" of LR lesions staying >1 hour in a 24 degrees C air-conditioned room. Safety assessments included monitoring and recording of all adverse events and tolerability to treatment. The follow-up period was 2.5 to 4.7 years.

Results: Ten women (median age, 22 years) were enrolled. Seven patients achieved "clear or almost clear" of LR lesions after CLS. The postoperative skin surface temperature increase was 7.4 degrees C +/- 2.6 degrees C. Two patients achieved "major partially resolved," and one patient achieved "minor partially resolved." Two of the seven with "clear or almost clear" results reported recurrence <= 1 year during the follow-up, CLS was repeated, and they then achieved "clear or almost clear" again. Two patients reported mild pain localized to the thigh area, which resolved spontaneously by the second day.

Conclusions: This study showed CLS provides a valid option for the treatment of idiopathic LR. The efficacy of CLS can be long-lasting, and CLS can be repeated if LR recurs. Targeting at gray rami communicans, rather than the sympathetic trunk, is comparably effective and safer for sympathetic interruption.

语种: 英语
所属项目编号: 77434-01 ; YETP0072
项目资助者: Peking University Third Hospital Seed Funding ; Beijing Higher Education Young Elite Teacher Project
WOS记录号: WOS:000361885800028
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60684
Appears in Collections:北京大学第三临床医学院_皮肤科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Peking Univ, Hosp 3, Dept Dermatol, Beijing 100191, Peoples R China
2.Peking Univ, Hosp 3, Dept Intervent Radiol & Vasc Surg, Beijing 100191, Peoples R China

Recommended Citation:
Wang, Wen-Hui,Zhang, Long,Li, Xuan,et al. Chemical lumbar sympathectomy in the treatment of idiopathic livedo reticularis[J]. JOURNAL OF VASCULAR SURGERY,2015,62(4):1018-1022.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Wang, Wen-Hui]'s Articles
[Zhang, Long]'s Articles
[Li, Xuan]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Wang, Wen-Hui]‘s Articles
[Zhang, Long]‘s Articles
[Li, Xuan]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace