IR@PKUHSC  > 北京大学第一临床医学院
学科主题临床医学
Epidural Labor Analgesia Is Associated with a Decreased Risk of Postpartum Depression: A Prospective Cohort Study
Ding, Ting1; Wang, Dong-Xin1; Qu, Yuan1; Chen, Qian2; Zhu, Sai-Nan3
刊名ANESTHESIA AND ANALGESIA
2014-08-01
DOI10.1213/ANE.0000000000000107
119期:2页:383-392
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Anesthesiology
资助者Peking University First Hospital ; Peking University First Hospital
研究领域[WOS]Anesthesiology
关键词[WOS]EDINBURGH POSTNATAL DEPRESSION ; CESAREAN DELIVERY ; CHINESE WOMEN ; ACUTE PAIN ; CHILDBIRTH ; SCALE ; MOTHERS ; PSYCHOPATHOLOGY ; INSTRUMENTS ; VALIDATION
英文摘要

BACKGROUND: Postpartum depression is a common psychiatric disorder in parturients after delivery. The etiology remains unclear, and multiple factors may be involved. In this study, we investigated whether epidural labor analgesia was associated with a decreased risk of postpartum depression development.

METHODS: Two hundred fourteen parturients who were preparing for a vaginal delivery were enrolled in this prospective cohort study. Epidural labor analgesia was performed in 107 of 214 patients on their request. Parturients′ mental status was assessed with the Edinburgh Postnatal Depression Scale at 3 days and 6 weeks after delivery. A score of 10 or higher on the scale at 6 weeks was used as an indication of postpartum depression. Parturients′ characteristics together with perinatal variables were collected. Multivariate logistic regression analysis was performed to assess an association between the use of epidural analgesia and the occurrence of postpartum depression.

RESULTS: Postpartum depression occurred in 14.0% (15 of 107) of parturients who received epidural labor analgesia and in 34.6% (37 of 107) of those who did not (P < 0.001). Use of epidural labor analgesia was associated with a decreased risk of postpartum depression (odds ratio [OR] 0.31, 95% confidence interval [CI], 0.12-0.82, P = 0.018). Attendance at childbirth classes during pregnancy (OR 0.30, 95% CI, 0.12-0.79, P = 0.015) and continued breast-feeding after delivery (OR 0.02, 95% CI, 0.00-0.07, P < 0.001) were also associated with decreased risks of postpartum depression. A high Edinburgh Postnatal Depression Scale score at 3 days postpartum was associated with an increased risk of postpartum depression (OR 1.20, 95% CI, 1.05-1.37, P = 0.009).

CONCLUSIONS: Epidural labor analgesia was associated with a decreased risk of postpartum depression. Further study with a large sample size is needed to evaluate the impact of epidural analgesia on the occurrence of postpartum depression.

语种英语
资助者Peking University First Hospital ; Peking University First Hospital
WOS记录号WOS:000339455900021
Citation statistics
Cited Times:23[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60723
Collection北京大学第一临床医学院
作者单位1.Peking Univ, Hosp 1, Dept Anesthesiol & Surg Intens Care, Beijing 100034, Peoples R China
2.Peking Univ, Hosp 1, Dept Gynecol & Obstet, Beijing 100034, Peoples R China
3.Peking Univ, Hosp 1, Dept Biostat, Beijing 100034, Peoples R China
Recommended Citation
GB/T 7714
Ding, Ting,Wang, Dong-Xin,Qu, Yuan,et al. Epidural Labor Analgesia Is Associated with a Decreased Risk of Postpartum Depression: A Prospective Cohort Study[J]. ANESTHESIA AND ANALGESIA,2014,119(2):383-392.
APA Ding, Ting,Wang, Dong-Xin,Qu, Yuan,Chen, Qian,&Zhu, Sai-Nan.(2014).Epidural Labor Analgesia Is Associated with a Decreased Risk of Postpartum Depression: A Prospective Cohort Study.ANESTHESIA AND ANALGESIA,119(2),383-392.
MLA Ding, Ting,et al."Epidural Labor Analgesia Is Associated with a Decreased Risk of Postpartum Depression: A Prospective Cohort Study".ANESTHESIA AND ANALGESIA 119.2(2014):383-392.
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