IR@PKUHSC  > 北京大学基础医学院  > 病原生物学系
学科主题基础医学
Pathogenicity of GB virus C on virus hepatitis and hemodialysis patients
Zhu, WF; Yin, LM; Li, P; Huang, L; Zhuang, H
刊名WORLD JOURNAL OF GASTROENTEROLOGY
2003-08-01
9期:8页:1739-1742
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Gastroenterology & Hepatology
研究领域[WOS]Gastroenterology & Hepatology
关键词[WOS]INFECTION ; PREVALENCE ; C/HGV ; HGV ; EPIDEMIOLOGY ; DISEASES ; BIOLOGY ; LIVER
英文摘要

AIM: To determine the pathogenicity of GB virus C (GBV-C) on liver and the effects of its co-infection on the clinical features and prognosis of patients with hepatitis B and C.

METHODS: Cross-sectional study was carried out in 413 patients with acute, chronic hepatitis B or liver cirrhosis, and in 67 hemodialysis patients. A 20-month prospective cohort study was carried out in 95 hepatitis B and 80 hepatitis C patients. A reverse transcriptase nested polymerase chain reaction (RT-nPCR) of the 5-noncoding region was used to detect circulating GBV-C RNA. Liver function was determined by an automated analyzer for all patients.

RESULTS: The prevalence of GBV-C in the high-risk populations with the virus transmitted via blood was high, ranging from 16.2 to 28.8 %. Co-infection with GBV-C in hepatitis B patients did not affect the clinical features of the disease or liver function. The dialysis patients infected with GBV-C alone did not develop functional changes to the liver. Prospective cohort study showed that GBV-C co-infection did not affect the clinical features, prognosis or negative serum conversion rate of chronic hepatitis B and C.

CONCLUSION: The results suggest that GBV-C has no marked pathogenicity on liver, so it may not be a hepatitis virus.

语种英语
WOS记录号WOS:000184963600018
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
版本出版稿
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60765
专题北京大学基础医学院_病原生物学系
作者单位Beijing Univ, Sch Basic Med Sci, Dept Microbiol, Beijing 100083, Peoples R China
推荐引用方式
GB/T 7714
Zhu, WF,Yin, LM,Li, P,et al. Pathogenicity of GB virus C on virus hepatitis and hemodialysis patients[J]. WORLD JOURNAL OF GASTROENTEROLOGY,2003,9(8):1739-1742.
APA Zhu, WF,Yin, LM,Li, P,Huang, L,&Zhuang, H.(2003).Pathogenicity of GB virus C on virus hepatitis and hemodialysis patients.WORLD JOURNAL OF GASTROENTEROLOGY,9(8),1739-1742.
MLA Zhu, WF,et al."Pathogenicity of GB virus C on virus hepatitis and hemodialysis patients".WORLD JOURNAL OF GASTROENTEROLOGY 9.8(2003):1739-1742.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Pathogenicity of GB (93KB)期刊论文出版稿开放获取CC BY-NC-SA浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Zhu, WF]的文章
[Yin, LM]的文章
[Li, P]的文章
百度学术
百度学术中相似的文章
[Zhu, WF]的文章
[Yin, LM]的文章
[Li, P]的文章
必应学术
必应学术中相似的文章
[Zhu, WF]的文章
[Yin, LM]的文章
[Li, P]的文章
相关权益政策
暂无数据
收藏/分享
文件名: Pathogenicity of GB virus C on virus hepatitis and hemodialysis patients.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。