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学科主题: 口腔医学
题名:
Adenomatous ductal proliferation of the salivary gland
作者: Yu, GY; Donath, K
刊名: ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS
发表日期: 2001-02-01
卷: 91, 期:2, 页:215-221
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Dentistry, Oral Surgery & Medicine
研究领域[WOS]: Dentistry, Oral Surgery & Medicine
关键词[WOS]: CYCLING CELLS ; MORPHOGENESIS ; PATHOBIOLOGY ; HISTOGENESIS ; HYPERPLASIA ; NEOPLASIA ; TUMORS
英文摘要:

Objective, The objective of this study is to report a series of patients with adenomatous ductal proliferation of the salivary gland and to investigate the nature and histogenesis of this process.

Study design. The histologic and immunohistochemical studies of 13 patients with adenomatous ductal proliferation of the salivary gland were performed.

Results. Ten cases coexisted with other diseases, such as salivary gland tumor or chronic parotitis. Most of the lesions were limited to 1 or 2 lobules and showed prominent ductal proliferation with some acinar cell complexes. The proliferative ducts had a compact growth pattern with little stroma. Dedifferentiation of acinar cells, identified by the loss of their secretory granules and appearing similar to intercalated duct epithelium, was seen in the early stages of adenomatous ductal proliferation.

Conclusion. Acinar cells play a role in the histogenesis of salivary gland tumors because acinar cells clearly participate in the formation of the proliferative ducts.

语种: 英语
WOS记录号: WOS:000167051300018
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60800
Appears in Collections:北京大学口腔医学院_期刊论文

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作者单位: 1.Peking Univ, Sch Stomatol, Dept Oral & Maxillofacial Surg, Beijing 100081, Peoples R China
2.Univ Hamburg, Inst Pathol, Dept Oral Pathol, Hamburg, Germany

Recommended Citation:
Yu, GY,Donath, K. Adenomatous ductal proliferation of the salivary gland[J]. ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS,2001,91(2):215-221.
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